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Effectiveness of the Bivalent mRNA Vaccine in Preventing Severe COVID-19 Outcomes: An Observational Cohort Study
SSRN (The Lancet) ^ | Ronen Arbel, Abel Peretz, et al.

Posted on 01/09/2023 6:56:56 PM PST by semimojo

Background: During Late 2022, the SARS-CoV-2 Omicron BA.5 sublineages accounted for most of the sequenced viral genomes worldwide. Bivalent mRNA vaccines contain an ancestral SARS-CoV-2 strain component plus an updated component of the Omicron BA.4/BA.5. Since September 2022, a single bivalent booster dose has been recommended for adults who have completed a primary vaccination series and are at high risk for severe Covid-19 disease. Evidence regarding the effectiveness of the bivalent vaccine in reducing hospitalizations and death due to Covid-19 is warranted.

Methods: This retrospective cohort study included all members of Clalit Health Services, aged ≥65, eligible for a bivalent booster. Hospitalizations and death due to Covid-19 among participants who received the bivalent vaccine were compared with those who did not. A Cox proportional-hazards regression model with time-dependent covariates was used to estimate the association between the bivalent vaccine and Covid-19 outcomes while adjusting for demographic factors and coexisting illnesses.

Findings: A total of 622,701 participants met the eligibility criteria. Of those, 85,314 (14%) received a bivalent-booster during the 70-day study period. Hospitalization due to Covid-19 occurred in 6 bivalent recipients and 297 participants who did not, adjusted hazard ratio (HR): 0.19 (95% CI, 0.08-0.43). Death due to Covid-19 occurred in 1 bivalent recipient and 73 participants who did not, adjusted HR 0.14: (95% CI, 0.02-1.04).

Interpretation: Participants who received the bivalent vaccine had lower hospitalization and mortality rates due to Covid-19 than non-recipients up to 70 days after vaccination.


TOPICS: Health/Medicine; Science
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Israeli study.

Compared to vaccinated folks who had NOT gotten bivalent:

Older folks who got the bivalent had 81% reduction in hospitalizations 86% reduction in deaths

1 posted on 01/09/2023 6:56:56 PM PST by semimojo
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To: semimojo

I gotta song (unfinished) called, WUHAN VACCINE AGAIN (played to the tune of “Werewolves of London”).

https://www.youtube.com/watch?v=nvN56FD6-vg

Common, everybody sing along…

(Second verse)
You hear them howling around your kitchen door.
Better not let them in.
Young people dropping like flies
Wuhan Vaccine again

Aah-hoo Wuhan Vaccine
Aah-hoo
Aah-hoo Wuhan Vaccine
Aah-hoo… huh!

(Middle of third verse)
You better stay away from them
They’ll clog your arteries Jim
I’d like to meet their accountants

Aah-hoo Wuhan Vaccine
Aah-hoo
Aah-hoo Wuhan Vaccine
Aah-hoo…

I saw a Globalist walking with the Queen
Doing the Wuhan Vaccine
I saw the son of a Globalist walking with the Queen
Doing the Wuhan Vaccine

Aah-hoo Wuhan Vaccine
Aah-hoo
Aah-hoo Wuhan Vaccine
Aah-hoo…


2 posted on 01/09/2023 7:00:02 PM PST by Jim W N (MAGA by restoring the Gospel of the Grace of Christ (Jude 3) and our Free Constitutional Republic!)
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To: semimojo

What about not vaccinated people?


3 posted on 01/09/2023 7:00:16 PM PST by frogjerk (More people have died trusting the government than not trusting the government.)
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To: semimojo
up to 70 days after vaccination

So what about after that?

Not addressed? We're supposed to just be shot up every 70 days?

4 posted on 01/09/2023 7:01:21 PM PST by Golden Eagle (The LGBT indoctrination agenda is designed to outlaw the Bible, and anyone who follows it.)
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To: semimojo

What about the absolute numbers?

1 is close to an 86% reduction of 2.


5 posted on 01/09/2023 7:01:47 PM PST by Paladin2
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To: semimojo
Interesting.

Also interesting they limit it to those 65 and older.

6 posted on 01/09/2023 7:01:54 PM PST by marktwain
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To: frogjerk

I’d like to know as well.


7 posted on 01/09/2023 7:03:00 PM PST by peggybac (My will is what I wanted. God's will is what I got.)
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To: semimojo

86% reduction in mortality in patients 65 or older works for me


8 posted on 01/09/2023 7:05:15 PM PST by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: frogjerk
Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status

This Israeli study didn't look at that but there's a wealth of data here:

Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status

In November hospitalizations were 16X higher in the unvaccinated.

9 posted on 01/09/2023 7:05:45 PM PST by semimojo
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To: Paladin2
What about the absolute numbers?

"A total of 622,701 participants met the eligibility criteria. Of those, 85,314 (14%) received a bivalent-booster during the 70-day study period. Hospitalization due to Covid-19 occurred in 6 bivalent recipients and 297 participants who did not.

10 posted on 01/09/2023 7:07:21 PM PST by semimojo
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To: blueplum
86% reduction in mortality in patients 65 or older works for me

So you're willing to be shot up, every ~2 months, for something you might not even catch?

11 posted on 01/09/2023 7:08:39 PM PST by Golden Eagle (The LGBT indoctrination agenda is designed to outlaw the Bible, and anyone who follows it.)
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To: semimojo
70-day study period

Tiny. There's 5 (five) periods of that length in a single year. So you'd need 5 shots to just make it through a year, to maintain that level of effectiveness, best case.

Where are the results regarding the dangers of taking this shot, every 70 days?

12 posted on 01/09/2023 7:12:25 PM PST by Golden Eagle (The LGBT indoctrination agenda is designed to outlaw the Bible, and anyone who follows it.)
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To: semimojo

Thanks.

Seems like definitive numbers, though both a very low number of the study population.


13 posted on 01/09/2023 7:13:16 PM PST by Paladin2
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To: Paladin2
...though both a very low number of the study population.

True. You'll be dealing with very low overall hospitalization rates with a vaccinated population like this.

14 posted on 01/09/2023 7:16:06 PM PST by semimojo
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To: semimojo

Not only is the Covid mRNA vaccine a death jab, but Lancet is without any credibility due to their past misconduct.


15 posted on 01/09/2023 7:16:18 PM PST by devere
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To: Golden Eagle

.... and what are the effects of that on the immune system?...


16 posted on 01/09/2023 7:19:01 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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To: semimojo

I can see where the 86% number comes from.

Both hospitalization percentages are very low

Now I suppose this analysis has to factor in Age, Sex, and “preexisting” conditions, plus perhaps more factors.


17 posted on 01/09/2023 7:21:17 PM PST by Paladin2
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To: semimojo
You'll be dealing with very low overall hospitalization rates with a vaccinated population like this.

Only if you have a very high deployment rate.

A deployment rate that equals distributed shots to most Americans every 70 days.

Not realistic, to say the least. Independent of the unknown dangers of a shot rate reaching that frequency, which you haven't yet addressed.

18 posted on 01/09/2023 7:24:25 PM PST by Golden Eagle (The LGBT indoctrination agenda is designed to outlaw the Bible, and anyone who follows it.)
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To: Paladin2
Now I suppose this analysis has to factor in Age, Sex, and “preexisting” conditions, plus perhaps more factors.

I don't think so.

This retrospective cohort study included all members of Clalit Health Services, aged ≥65, eligible for a bivalent booster.

It doesn't look like they did much additional screening. I don't know what the booster eligibility requirements are in Israel but it's usually only that it's been long enough since your last shot.

19 posted on 01/09/2023 7:27:20 PM PST by semimojo
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To: semimojo
It doesn't look like they did much additional screening. I don't know what the booster eligibility requirements are

It's time to admin you and this study weren't ready for prime time analysis.

20 posted on 01/09/2023 7:32:07 PM PST by Golden Eagle (The LGBT indoctrination agenda is designed to outlaw the Bible, and anyone who follows it.)
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