Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Eat right, live longer: Could a moderate protein diet be the coveted elixir of youth? (25% - 35% of calories)
Medical Xpress / Waseda University / GeroScience ^ | May 31, 2023 | Yoshitaka Kondo et al

Posted on 06/02/2023 1:53:51 PM PDT by ConservativeMind

In a new study, a team led by Assistant Professor Yoshitaka Kondo investigated the amount of dietary protein needed to improve metabolic health in mice approaching old age.

The team recruited young (6 months old) and middle-aged (16 months old) male C57BL/6NCr mice who were fed isocaloric diets with varying protein content (5 to 45 %) for two months. After two months, the effect of varying protein diets was assessed based on measurements of skeletal muscle weight, liver and plasma lipid profiles, and self‑organizing map (SOM) cluster analysis of plasma amino acid profiles.

The team observed that the consumption of a low-protein diet led to the development of mild fatty liver, with increased levels of hepatic lipids in middle-aged mice as compared to young mice. In contrast, a moderate-protein diet led to reduced blood glucose concentrations and lipid levels in both liver and plasma. These findings indicate that a moderate-protein diet (25% and 35%) kept both young and middle-aged mice metabolically healthier.

On examining the effect of varying protein diets on plasma amino acid concentrations in mice of both age groups, the researchers observed that the plasma concentration of individual amino acids varied with age and varying dietary protein content. Furthermore, the plasma amino acid profiles revealed using SOM analysis showed the correlation between different protein intake and the varying amounts of hepatic triglycerides and cholesterol levels.

Kondo remarks, "Protein requirements change through the course of life, being higher in younger reproductive mice, reducing through middle age, and rising again in older mice as protein efficiency declines. The same pattern is likely to be observed in humans. Therefore, it could be assumed that increasing daily protein intake in meals could promote metabolic health of people. Moreover, ideal dietary macronutrient balance at each life stage could also extend health span."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: adequateprotein; diet; protein; proteindiet
Navigation: use the links below to view more comments.
first 1-2021-24 next last
We stop efficiently using and making proteins, as we age.

Many critical processes depend on the amino acids that make up proteins.

1 posted on 06/02/2023 1:53:51 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 06/02/2023 1:54:16 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

They recruited the mice? How?


3 posted on 06/02/2023 1:56:03 PM PDT by Reno89519 (Donald Tantrum? No Thank You. We Can Do Better! I am a Veteran Supporting Veteran DeSantis.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

We need fiber and veges, but protein diets are life.

I laugh at the vegans who stuff themselves full of vegetables and carbs - like cows - then wonder why they’re slow and fat.


4 posted on 06/02/2023 2:03:54 PM PDT by AAABEST ( NY/DC/CA media/political/military industrial complex DELENDA EST)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

A person needs protein for brain development and thus critical thinking. Anyone who is recommending a low protein diet wants you compliant and easy to control.

“Protein is the second largest matter in the brain, second only to water, so it is important to nourish your brain with protein rich foods. Proteins help neurons within the brain communicate with each other through neurotransmitters that are made from amino acids.”


5 posted on 06/02/2023 2:08:16 PM PDT by CFW (old and retired)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

All you have to do is observe design of teeth in any mammals to know how they evolved. If large canines are present (tigers, leopards) then you are designed to eat more meat proteins. If canines are not prominent and have good sized molars humans), then you evolved eating a mixed diet.

Another good indication is length of small intestine. Carnivores have much shorter intestines than herbivores (deers, cows). Humans are again somewher in the middle between the two.

We do not need to fund studies examining mice to know whats best diet. Just observe your anatomy.


6 posted on 06/02/2023 2:29:00 PM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: CFW

Elephants have larger brains than humans and they never eat meat protein.


7 posted on 06/02/2023 2:30:23 PM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: entropy12

They can digest cellulose, can you?


8 posted on 06/02/2023 2:32:50 PM PDT by Varda
[ Post Reply | Private Reply | To 7 | View Replies]

To: AAABEST

We evolved as omnivores: meat, eggs, fruits, veggies.

Grain is a relatively recent addition to our diets. It provides cheap calories but fewer essential nutrients.

I’m trying to keep my bread/pasta levels low.


9 posted on 06/02/2023 2:34:45 PM PDT by SauronOfMordor (The rot of all principle begins with a single compromise.)
[ Post Reply | Private Reply | To 4 | View Replies]

To: entropy12

Non sequitur response. We were debating need to eat animal protein for brain function. Elephants have good functioning brains without any animal protein.


10 posted on 06/02/2023 2:38:19 PM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: ConservativeMind; metmom
(From the article):" ..Therefore, it could be assumed that increasing daily protein intake in meals could promote metabolic health of people."

Tell that to the WEF, and the United Nations 2030 Agenda crowd, and other organizations that want us to eat insects.
Protein is brain food and is necessary among humans for survival and brain enrichment.

11 posted on 06/02/2023 2:38:41 PM PDT by Tilted Irish Kilt
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

We stop efficiently using and making proteins, as we age.
Many critical processes depend on the amino acids that make up proteins.
~~~~~

DHEA supplementation helps. As we age the adrenal glands reduce production of critical hormones which stimulate cellular processing of amino acids. DHEA is the body’s adrenal anabolic steroid which stimulates proper release and uptake of these hormones. DHEA production fades with age.


12 posted on 06/02/2023 2:40:08 PM PDT by nagant (`)
[ Post Reply | Private Reply | To 1 | View Replies]

To: SauronOfMordor

You are correct. Grains were produced by agriculture going back only 15,000 years. Humans and humanoids have been around much longer by orders of magnitude.


13 posted on 06/02/2023 2:40:08 PM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
[ Post Reply | Private Reply | To 9 | View Replies]

To: entropy12

Elephants have larger brains than humans and they never eat meat protein.
~~~~~~

The superior intelligence of humans shows just how little good this aspect does for elephants. They can’t even pronounce or spell intelligence.


14 posted on 06/02/2023 2:44:11 PM PDT by nagant (`)
[ Post Reply | Private Reply | To 7 | View Replies]

To: entropy12

Grains were produced by agriculture going back only 15,000 years. Humans and humanoids have been around much longer by orders of magnitude.
~~~~~

Humans are Humans because of our ability to eat grains.

Over 2.5 million years (25 ice ages) ago humans evolved from primates which randomly started releasing DPPIV into their intestines. The mutation allowed hominids to grow and eat grains in agricultural communities, just like today. I can tie the rapid evolution of hominids to the subsequent release of zonulin into the intestines as a “viral marketing” strategy to induce epidemics and accelerate the process of evolution.


15 posted on 06/02/2023 2:58:15 PM PDT by nagant (`)
[ Post Reply | Private Reply | To 13 | View Replies]

To: ConservativeMind

Cool, grabbed a leg of lamb today.


16 posted on 06/02/2023 3:04:47 PM PDT by Pollard ( >>> The Great Rest is already underway! <<<)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Have archeologist found evidence of tranny cave women (men pretending their women) millions of years ago?


17 posted on 06/02/2023 3:06:46 PM PDT by Leep (What skill or service did the biden family have that netted them tens of millions of dollars?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Have archeologist found evidence of tranny cave women (men pretending they’re women) millions of years ago?


18 posted on 06/02/2023 3:07:17 PM PDT by Leep (What skill or service did the biden family have that netted them tens of millions of dollars?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind
One of my favorite Star Trek scenes. The Enterprise crew finds people who live thousands of years. Dr. McCoy investigates their blood/DNA, and states:

"Who knows? It might eventually cure the common cold, but lengthen lives? Poppycock! I can do more for you if you just eat right and exercise regularly."

19 posted on 06/02/2023 3:36:05 PM PDT by Ronaldus Magnus III (Do, or do not, there is no try)
[ Post Reply | Private Reply | To 1 | View Replies]

To: entropy12

You brought up animal protein, the article just references protein. There is plenty of protein in the grasses and leaves and bushes elephants eat. There is minimal protein in fruit but elephants eat that too.

Research has shown that all plants contain protein and at least 14% of the total calories of every plant are protein.


20 posted on 06/02/2023 4:13:58 PM PDT by chuck allen
[ Post Reply | Private Reply | To 10 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-24 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson