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Commonly used gout drug found effective against COVID-19 (Probenecid)
Medical Xpress / University of Georgia / Viruses ^ | July 27, 2023 | David Mitchell / David E. Martin et al

Posted on 07/30/2023 8:14:36 AM PDT by ConservativeMind

An anti-inflammatory drug commonly used to treat gout could significantly improve outcomes in patients with mild-to-moderate COVID-19 infections, according to research by a team led by Ralph Tripp.

In a dose-range study of probenecid, researchers showed significant improvements both in preventing the transmission of COVID-19 and the speed at which symptoms cleared in patients. In comparison to other FDA-approved drugs used to treat the virus, probenecid helped clear symptoms several days faster, Tripp said.

"This is a significant development," said Tripp. "It shows improvement in both virus clearance and symptom reduction."

TrippBio enrolled 75 non-hospitalized patients with mild-to-moderate COVID-19. The patients were divided into three groups: one receiving 500 milligrams of probenecid twice daily, another receiving 1,000 mg twice daily and a third receiving a placebo twice daily for five days. Symptoms were recorded incrementally over the course of 28 days to assess progress.

None of the 75 patients who completed the study were hospitalized, and the group receiving the twice-daily 500 mg treatment showed a two-day improvement (nine days compared to 11) in viral clearance over the placebo. Importantly, the 1,000 mg treatment doubled the clearance improvement to four days, resulting in an average recovery time of seven days. Patients treated with probenecid also showed improvements within three to five days after contracting the virus.

The most effective treatment, Tripp said, is for patients to take 1,000 mg tablets twice daily for approximately five days.

The study included patients aged 18-65 who experienced mild to moderate symptoms.

Tripp also suggested testing was needed to confirm the effectiveness of the drug against other respiratory viruses. The drug has shown strong activity against both influenza and respiratory syncytial virus (RSV) in laboratory and animal studies.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: chinavirustreatment; covid; gout; gouttreatment; virus
This is available today. The brand name is “Probalan.”

Apparently, this is being considered relatively safe for children and older people.

1 posted on 07/30/2023 8:14:36 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 07/30/2023 8:15:11 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I thought they said the steroid/non-steroid treatments increased the chance of developing pneumonia/cytokine storm?


3 posted on 07/30/2023 8:17:16 AM PDT by Skywise
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To: ConservativeMind
I've yet to personally hear about anyone under 18 being very ill from COVID. Maybe others have.

So, how long before WHO and the CDC outlaw the use of this drug in treating COVID?

4 posted on 07/30/2023 8:18:40 AM PDT by CatOwner (Don't expect anyone, even conservatives, to have your back when the SHTF in 2021 and beyond.)
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To: CatOwner

Can’t wait for the outcry that prescribing this to treat ( operative term TREAT which nullifies EUA of experimental drugs like the vaxx used when there is no treatment) …will deprive gout patients of their drugs


5 posted on 07/30/2023 8:23:03 AM PDT by silverleaf (It's not propaganda just because you disagree with it. )
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To: ConservativeMind

I wrote a short ebook on long covid treatments. One thing I discovered in the course of my research was that one consequence of aging Is inflammation. That everything from auto immune and chronic disease to high I bmi to household mold To old embedded viruses increase inflammation. People with those pre existing conditions can be wiped out by covid. The consequences are death or long covid


6 posted on 07/30/2023 8:39:16 AM PDT by ckilmer (ui)
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To: ConservativeMind

.


7 posted on 07/30/2023 8:53:53 AM PDT by sauropod (Sun Tzu: “The supreme art of war is to subdue the enemy without fighting”)
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To: ConservativeMind

It appears tons of drugs , vitamins etc are effective against COVID except their Deadly Vaccine


8 posted on 07/30/2023 9:07:14 AM PDT by butlerweave
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To: ConservativeMind

Interesting last line: “The drug has shown strong activity against both influenza and respiratory syncytial virus (RSV) in laboratory and animal studies.”

We just got back from our first-ever cruise. Four of the six in our party got a respiratory virus on the fourth day of seven days. We have common cold symptoms. Our 34 year old daughter lost her voice. I’m sitting here right now feeling really yucky and blah with mild cold symptoms.

RSV and influenza are the most common illnesses caught on cruises, so the use of probenecid for RSV caught my attention. Wiki says that “treatment for RSV is primarily supportive, including oxygen therapy and breathing support (CPAP or nasal high flow oxygen). In cases of severe respiratory failure, intubation and mechanical ventilation may be required.”


9 posted on 07/30/2023 9:13:59 AM PDT by ProtectOurFreedom (We are proles, they are nobility.)
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To: ConservativeMind
From 2008...

Thrombocytopenia from Combination Treatment with Oseltamivir and Probenecid: Case Report, MedWatch Data Summary, and Review of the Literature

10 posted on 07/30/2023 9:25:07 AM PDT by mewzilla (We will never restore the republic if we don't first secure the ballot box.)
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To: butlerweave

It’s almost like the reason for pushing the vax was not at all about covid. Could it be money, population control, just plain control or something else.


11 posted on 07/30/2023 9:25:31 AM PDT by Dutch Boy (The only thing worse than having something taken from you is to have it returned broken. )
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To: CatOwner

“So, how long before WHO and the CDC outlaw the use of this drug in treating COVID?”

Choice of words is important to the CDC and WHO. When the original vaccines were put into place they did not treat covid. There has never been a vaccine to treat covid. The vaccines were used to make the body feel better during it’s duration when you got it. The vaccines didn’t kill a single virus unless they bored it to death. This new “discovery” does exactly the same. But as long as the medical bureaus of statistics like the WHO or the CDC can “con” the public into thinking anything will be better with their declarations that they equate to Moses and the separating of the Red Sea, they keep their highly overpaid jobs.

wy69


12 posted on 07/30/2023 10:05:39 AM PDT by whitney69
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To: CatOwner

“So, how long before WHO and the CDC outlaw the use of this drug in treating COVID?”

Choice of words is important to the CDC and WHO. When the original vaccines were put into place they did not treat covid. There has never been a vaccine to treat covid. The vaccines were used to make the body feel better during it’s duration when you got it. The vaccines didn’t kill a single virus unless they bored it to death. This new “discovery” does exactly the same. But as long as the medical bureaus of statistics like the WHO or the CDC can “con” the public into thinking anything will be better with their declarations that they equate to Moses and the separating of the Red Sea, they keep their highly overpaid jobs.

wy69


13 posted on 07/30/2023 10:05:39 AM PDT by whitney69
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To: ConservativeMind

Problem solved. Extra meds to use against Covid-1984 that really work!

Get on with your lives now!!!


14 posted on 07/30/2023 11:17:55 AM PDT by Delta 21 (MAGA Republican is my pronoun.)
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To: ConservativeMind

Gout? Try celery + ginger juice https://www.youtube.com/watch?v=Age_dvsJMRk

I am doing this right now.


15 posted on 07/30/2023 11:38:10 AM PDT by dennisw (Never attribute to incompetence-stupidity, that which is adequately explained by malice)
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To: dennisw

I’ll have to watch that. I have what is probably minor gout right now. Talk about painful when you kick a concrete step.


16 posted on 07/30/2023 1:38:35 PM PDT by cyclotic
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To: ConservativeMind

Not OTC.


17 posted on 07/30/2023 3:12:03 PM PDT by bgill
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