Posted on 10/16/2023 9:42:54 PM PDT by ConservativeMind
The pursuit of understanding the secrets behind exceptional longevity isn't easy. Now our recent study has unveiled some common biomarkers, including levels of cholesterol and glucose, in people who live past 90.
Our research included data from 44,000 Swedes who underwent health assessments at ages 64-99. These participants were then followed through Swedish register data for up to 35 years.
Twelve blood-based biomarkers related to inflammation, metabolism, liver and kidney function, as well as potential malnutrition and anemia, were included. All of these have been associated with aging or mortality in previous studies.
We found that, on the whole, those who made it to their hundredth birthday tended to have lower levels of glucose, creatinine and uric acid from their sixties onwards.
For example, very few of the centenarians had a glucose level above 6.5 earlier in life, or a creatinine level above 125.
When exploring which biomarkers were linked to the likelihood of reaching 100, we found that all but two (alat and albumin) of the 12 biomarkers showed a connection to the likelihood of turning 100.
The people in the lowest out of five groups for levels of total cholesterol and iron had a lower chance of reaching 100 years as compared to those with higher levels. Meanwhile, people with higher levels of glucose, creatinine, uric acid and markers for liver function also decreased the chance of becoming a centenarian.
For uric acid, for instance, the absolute difference was 2.5 percentage points. This means that people in the group with the lowest uric acid had a 4% chance of turning 100 while in the group with the highest uric acid levels only 1.5% made it to age 100.
(Excerpt) Read more at medicalxpress.com ...
The glucose level of 6.5 mmol/L = 117 mg/dL The creatinine level of 125 umol/L = 1.41 mg/dL
They also didn’t tend to have low cholesterol or iron and did not tend to have higher uric acid values.
They missed ‘whiskey’.
God bless you if it’s your goal to make 100+. But from what I’ve observed, the 90s are typically a pretty damned rough decade for most of those who make it there.
Interestingly, for these people, it wasn’t a problem.
They had fewer health issues, of any sort.
My grandmother only died in her mid-90s because of malpractice in a hospital. She was doing great until then, and was actually great in the hospital for a postponed hip repair, but they accidentally killed her with two separate drugs, which she told them felt wrong, then ignored her description of what was happening to her over the next half day, giving her increasing doses of morphine to block the destruction they’d caused, inside her.
Until then, she was driving herself around and still using a non-motorized push mower on her small lawn. She had all her mental faculties, too.
I am still absolutely frustrated at her death, many years later.
Don’t blindly trust doctors and nurses to do the right thing. Be glad they do, when they do well. Encourage them, but get second-opinions. Double check or sanity check everything. Trust, but verify. Use the Internet and friends to gather information to help. Get yourself and your loved ones out of there, as soon as is feasible.
That’s what I’ve observed, too. But now mad then you do,find an exception.
I just chatted with one of my mom’s dearest friends from childhood. She is 94, drives, plays bridge, canasta, and sharp as a tack.
I’ve seen lots in their 90s in very bad shape by late 90s.
I’m 87 and no -one believes it. Weigh 116, everything works and nothing hurts, was doing 14-minute miles on the treadmill five days a week until the idiot governor closed the gyms for covid.
Now I have a cardiologist. First time ever needed one. He told me there was a big uptick in heart problems when the gyms were closed. My goal and his is to get me back to those 14-minute miles five days a week.
My MD and my cardiologist both think I can live to be 100. I’m definite hoping so. I have great friends, lots of fun, and a young cat who should not get dumped at the humane society.
I laugh at the ‘experts’.
.
My father made it to two months shy of 93, but his last 4 years were not pretty. My FIL made it to 95, but his last 7 months were difficult.
My maternal grandmother made it to 87, then had a mild heart attack and was taken to the hospital. She was advised that she should consent to a streptokinase(?) injection to reduce the risk of a follow-on heart attack, and she declined. She had a second, fatal heart attack 2 hours later. I'm confident that she thought about the lives of those in her age cohort and contemplating recovery and rehab and whatever else might come down the pipe in terms of other maladies, and she just said it is time.
pneumonia is the blessing of the aged....there's some truth to that.
you sound like in great shape....keep it up...do not go gentle into that good night...
your grandmother had wisdom....
“a young cat who should not get dumped at the humane society.”
Yep, I am greatly motivated to stick around at least as long as my pet birds are still chirping.
My boss’ grandmother and her three sisters lived to be: 104, 106, 108, and 110. Now that would have been a study.
Wait, higher total cholesterol and Iron are good? Dang, that’s the opposite of what I’ve heard.
That’s great. As the Romans used to say, “Ad multos annos!” (To many years!).
Well, I’m 74 and feel I like my fifties, so “Ad multos annos!”
Hah! s/b “and I feel like my fifties” ... of course.
There is no free lunch.
I feel the same way about my grandmother. She joined my wife and I in Japan and got the full tour in her mid 80s, very active, and she had type 2 diabetes and cellulitis back then. She continued on until her early/mid 90s without walking assistance, but finally was put in a wheelchair by her living assistance place.
She finally was killed by the first injection of the vaxx at 99 (which was for her own good, right?), she had a stroke within a week, lingered for a week or so, then died. She was to be 100 in a few months, a former WAVEs through WW2 and she had met my mother in law in Japan, who was a child in Japan and had seen Osaka bombed by America.
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