Not Hamilton or any other of the realists. Isolationism then was to allow the nation to develop strength and not have it prematurely drawn into European wars which would divide our nation into pro French and anti-French factions and tear it apart.
Washington's Farewell Address (written by Hamilton) was a warning against secession not a call for permanent isolationism. He would be all in favor of playing our proper role in the world today.
Proper role? What is our proper role?