"Obese people have more receptors for endocannabinoids than thin people, said Dr. F. Xavier Pi-Sunyer, a professor of medicine at Columbia University and the principal investigator of a large rimonabant study in the United States and Canada. The drug does not completely block these receptors, Dr. Pi-Sunyer said.
"The idea of blocking these receptors worked in animals.
"For example, mice that were genetically engineered so they could not respond to endocannabinoids ate less and were thinner than normal. And when scientists at Sanofi-Aventis gave rimonabant to obese mice, the animals ate much less, lost 20 percent of their body weight, and had lower levels of blood glucose and lipids, risk factors for diabetes and heart disease.
"Rimonabant, said Dr. Jeffrey Friedman, an obesity researcher at Rockefeller University, "is the first in what I think will be a wave of rational therapies" that attack what has recently been learned about how eating is controlled. But with rimonabant, he said, "the issue is, what's the safety and efficacy?"
"The company says it has enrolled more than 13,000 subjects in clinical trials asking if the drug helps with
Sanofi-Aventis.....hhhmmmm, chart looks pretty good.....note to self - call broker......
bttt
Cool.
But I quit alcohol (I no longer will even take a single beer or a single glass of wine) by being part of a 12 step program, and I lost 60 lbs by walking a lot and eating small meals.
But still, a shortcut might be nice for some. And there's that additional 40 lbs I want to lose... :o)
Too good to be true?
Read: if something works this well, there just has to be some downside ;D
Obesity drug offers bit of hope, bundle of hype Kansas City Star (subscription), MO - |
Myths grow around drug for dieters San Jose Mercury News (subscription), CA - By Gina Kolata. To people who have struggled for a lifetime to lose weight, the new drug called rimonabant sounds like a dream come true. ... |
Anti-obesity medicine stirs up whirlwind of hopes Arizona Republic, AZ - To people who have struggled for a lifetime to lose weight, the new drug called rimonabant sounds like a dream come true. It will ... |
Weight-loss drug's hype may be myth Contra Costa Times (subscription), CA - By Gina Kolata. It will melt away fat, with weight around the waist and abdomen the first to go. It will increase levels of HDL, the good cholesterol. ... |
Sounds like a miracle drug
You sure this isn't a fake story
This is too terrible to think about. Can't get high and can't eat Oreo's?
I feel terrible seeing the new Carl's Jr. commercial of a Caddilac crashing into a deli. I must have a supersized new Pastrami Burger before I diet! :)
ping
How about diet and exercize instead of sloth and gluttony.
How complicated is that?
bump
Does it make your arms and legs fall off, cause you to sprout a 3rd eye on your buttocks, and grow long toenails?