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Bird flu virus: A crisis waiting to explode
The Financial Express ^ | August 20th, 2005 | Gauri Lakhanpal

Posted on 08/19/2005 6:48:25 PM PDT by Termite_Commander

Health experts claim bird flu is a ticking time bomb waiting to explode. Initially, it was seen as a few isolated cases in South-East Asia, may now be the beginnings of a global pandemic. The virus is spreading rapidly and has already reached as far as Russia. The World Health Organisation too has warned of the possibilities of a worldwide avian influenza outbreak. With no vaccine ready for commercial use, countries across the world have started stockpiling what limited drugs are available.

The world first heard of bird flu when it hit Hong Kong in 1997. The H5N1 strain of the virus caused severe respiratory problems for 18 people of which an alarming one-third died. Rapid destruction of Hong Kong’s entire poultry population reduced the chances of further direct transmission to humans and a possible epidemic. February 2003 saw 2 more cases of H5N1 avian influenza, which resulted in one death. But it was really the outbreak that came later that year which has culminated in the state of affairs today. Between December 2003 and now, more than a hundred human cases of bird flu have been reported across four countries in Asia - Indonesia, Cambodia, Vietnam and Thailand - the last two being among the worst hit. Fatalities have occurred in over half the infected patients. The total number of human infections seems insignificant given the time period. However, it is a series of factors related to these outbreaks that is causing concern. To date, there has been no evidence of human-to-human transmission - a development that could very quickly give rise to a pandemic.

However, many experts have expressed a fear that it may only be a matter of time before the deadly H5N1 strain of bird flu combines with the human influenza virus and mutates into a form that can be transmitted among people. And the H5N1 variety has already demonstrated a propensity to acquire genes from viruses infecting other animals like pigs.

Furthermore, despite the low level of human fatalities, tens of thousands of fowl have been infected. In most cases this has resulted in the relevant governments culling millions of birds to control the spread of the disease. Unfortunately, in some instances action was either delayed or not taken at all.

At the end of June this year, more than two hundred migratory geese tested positive for the H5N1 strain in Qinhai Lake in North Western China. But Beijing did not cull the infected birds claiming they were a rare and protected species and vaccinated them instead. However, birds that survive the infection excrete the virus for at least 10 days, orally and in faces, facilitating its further propagation. No more cases of bird flu have been reported in China since. But given the country’s track record, in particular its cover-up of Severe Acute Respiratory Syndrome (SARS), it is plausible that the true extent of the problem has been kept under wraps - a potentially explosive situation.

In the following six weeks, fowl in Siberia, Kazakhstan, Tibet, and Mongolia tested positive for avian influenza. Migratory birds, possibly from China, are being cited as the culprit. But the outbreak has been steadily moving westwards. Most recently it struck Chelyabinksk a major industrial region in the Ural Mountains in Russia, which separate the European and Asian parts of the country.

These birds in Russia will soon leave to winter in warmer climates which will expose the Middle East, Africa, Australia, the West Coast of the US and of course India to the threat of bird flu. So far, human casualties have been limited both in terms of numbers and geographic scope.

But a broad geographical distribution of H5N1 increases the likelihood of dual infections leading to recombination that can produce a pandemic version of the virus that can be transmitted from human-to-human.

The situation is further complicated by the absence of a commercially viable avian influenza vaccine for humans. Currently, the only known treatment is the flu drug oseltamivir which Roche produces under the name Tamiflu. This can protect against infection but not treat those who are sick.

The fact that several Western countries have started stockpiling the drug is testament to the fact that the world is taking the threat seriously. The US has enough Tamiflu to treat 2.3 million people and is working to acquire more. Britain, France, Finland and Norway are placing orders that would cover up to 40% of their populations. The World Health Organisation is in talks to build a reserve of drugs for poorer countries.

Epidemiologists predict a flu pandemic will emerge three or four times every hundred years. Two of the last three global pandemics have originated in Asia. Outbreaks of the Asian flu in 1957-58 and the Hong Kong flu in 1968-69 killed over a million people. Spanish flu killed 40 million people world wide in 1918-1919.


TOPICS: News/Current Events
KEYWORDS:
We can only hope those vaccines that are in development will still be effective when H5N1 mutates, and that we have enough doses to slow or stop this thing.

By the way, a little factoid here. During the Spanish Flu Pandemic, one fifth of the population of earth was infected. And that was back in 1918 too.
1 posted on 08/19/2005 6:48:26 PM PDT by Termite_Commander
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To: Termite_Commander

Time to close off the borders--to birds.


2 posted on 08/19/2005 6:51:29 PM PDT by Brilliant
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To: Termite_Commander
Anyone remember the three books the President is reading on his Crawford vacation.

One of them was about a closely related subject.

Not a coincidence IMHO.
3 posted on 08/19/2005 7:22:45 PM PDT by BenLurkin (O beautiful for patriot dream - that sees beyond the years)
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To: Termite_Commander

I think we've come a long way since 1918.....in cleanliness, hygiene, prevention, etc......


4 posted on 08/19/2005 7:29:39 PM PDT by goodnesswins (Our military......the world's HEROES!)
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To: Termite_Commander
More little factoids: The 1918 Spanish Flu was spread by birds first and then by humans-to-humans. It was active for nearly five years. Nearly 50 million died. Bird Flu Reports
5 posted on 08/19/2005 7:42:37 PM PDT by ex-Texan (Mathew 7:1 through 6)
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To: Brilliant

Time to close off the borders to Asians!


6 posted on 08/19/2005 7:51:29 PM PDT by F14 Pilot (Democracy is a process not a product)
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To: goodnesswins
>I think we've come a long way since 1918.....in cleanliness, hygiene, prevention, etc......


Cleanliness has little to do with influenza. This is not spread fecal-oral.

I have been praying for the last 6 months that this doesn't hit before an effective vaccine is produces. This may be rumor but I have read that China tried to control the virus by feeding their chickens amantadine. If that is true, this bugger will be resistant to the fall-back anti-viral medicines.

Don't underestimate this bug. If it is as bad as it looks like it may be, you will lose someone you love. I'm a physician hold a Master's in Public Health and I'm boarded through the American Board of Preventive Medicine, this thing has me scared for my family and friends.
7 posted on 08/19/2005 7:54:24 PM PDT by dangerdoc (dangerdoc (not actually dangerous any more))
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To: goodnesswins
Well, we in America have, but in many places, like Asia or Africa it's a different story. If (or when, rather) a pandemic breaks out, those parts of the globe will be decimated.

It's really terrible thinking about what would happen in a third-world city in such a scenario.
8 posted on 08/19/2005 7:54:51 PM PDT by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: dangerdoc
Dangerdoc, I think that amantadine thing was confirmed by the WHO.

Count on the commies to screw things up.
9 posted on 08/19/2005 7:56:33 PM PDT by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: ex-Texan

Scary. A pandemic or global epidemic is an outbreak of an infectious disease that affects
people or animals over an extensive geographical area.

Influenza that caused several waves of pandemic in 1918–1919, resulting in ...
Medical definition of Spanish flu

More and more epidemics...pandemics...whatever--scares the heck out of this girl!


10 posted on 08/19/2005 7:57:26 PM PDT by Brynna77
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To: ex-Texan
Speaking of factoids, here's a page chock full of them.

The Influenza Pandemic of 1918
11 posted on 08/19/2005 8:02:13 PM PDT by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: dangerdoc
I have been praying for the last 6 months that this doesn't hit before an effective vaccine is produces.

According to someone interviewed on CNN just about a half hour ago, they have come up with a vaccine that appears, at first glance, to work. The only problem is that so much of it is required to protect an individual that the entire amount being delivered to the US government will only protect a few hundred thousand people.

(This doctor was discussing both vaccines and treatments, so I might be confusing the vaccine with the treatment. I'll have to wait until the Newsnight transcript is posted tomorrow morning to be sure.)

12 posted on 08/19/2005 8:02:43 PM PDT by Dont Mention the War (John Bolton for White House Press Secretary!)
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To: Dont Mention the War
The only problem is that so much of it is required to protect an individual that the entire amount being delivered to the US government will only protect a few hundred thousand people.

Luckily I am in the National Guard so I will be at the front of the line to get this. Hopefully liberal hippy social workers will be at the back of the line.
13 posted on 08/19/2005 8:04:39 PM PDT by Tailback (USAF distinguished rifleman badge #300, German Schutzenschnur in Gold)
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To: Termite_Commander
a little factoid here. During the Spanish Flu Pandemic,
Two questions:

1) What were health/hygiene practices like back then?

2) What are the health/hygiene practices like in South-East Asia?

14 posted on 08/19/2005 8:06:46 PM PDT by _Jim (Listening 28.400 MHz USB most every day now ...)
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To: dangerdoc

Okay.....guess it's another reason for my hubbie and I to take off for the hinterlands......away from the big cities, which, I'm sure will be hardest hit. And, I'm not one of those who likes to get shot up with the latest virus du jour.....I'm still not convinced the flu shot pushed on people every year really helps....having a STRONG immune system, however, would seem to help in ANY situation like this.


15 posted on 08/19/2005 8:37:40 PM PDT by goodnesswins (Our military......the world's HEROES!)
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To: Termite_Commander

Hmmmm.....sounds like Muslims would be hit hardest.....


16 posted on 08/19/2005 8:39:00 PM PDT by goodnesswins (Our military......the world's HEROES!)
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To: Brilliant
Yeh, but some FReepers will be still concerned only with SOuthern borders.
17 posted on 08/19/2005 8:56:57 PM PDT by ExitPurgamentum
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To: goodnesswins
BINGO!!!

That is the info I just received for in a newsletter I've been getting the past 10 years from a homeopathic doctor,(DR. David Williams).Here is an excerpt:

Protection from this form of flu boils down to having a healthy immune system and using such supplements as vitamin C and selenium and essential oils(tea tree and eucalyptus) in vaporizers.

I believe more info can be found at his web-site (drdavidwilliams.com)

18 posted on 08/19/2005 9:04:16 PM PDT by SweetCaroline (Experience is what you get when you didn't get what you wanted!!)
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To: SweetCaroline; All

Here's a link all of you might be interested in perusing:

Avian Flu Preparedness Project
http://www.freerepublic.com/focus/f-news/1453571/posts

Lots of ideas there about flu prevention and related topics.


19 posted on 08/19/2005 10:48:15 PM PDT by little jeremiah (A vitiated state of morals, a corrupted public conscience, are incompatible with freedom. P. Henry)
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