When my wife's cousin was pregnant, the doctors told her early on that her daughter would be born profoundly mentally retarded and disabled...that was 7 years ago...
Fortunately, my wife's cousin put her faith in G-d to do what He would...and today her daugther is a happy, healthy, beautiful 6 year old
My cousin had a similar experience. She was very nervous about her pregnancy because she had been born with a severe cleft palate. She's undergone, numerous surgeries to repair it. The doctors did amniocentesis with both her pregnancies. Her daughter was fine. But her son's came back with extremely bad results. I can't remember what my aunt, who is a nurse, called it. It's wasn't Down's Syndrome, but it did have to do with an extra chromosome. I believe it was the sixteenth chromosome. My aunt said that this particular defect caused horrible deformation, and often death. Anyhow, my cousin gave birth to a perfectly healthy boy. He's 18 now, and about to start college on a full academic scholarship.