If he had some elective experience, I'd say "right on"! It would be a great choice. But the country hasn't ever had a person who didn't come from the military, a Senator or a Governor as President. There's always a first time, I'm just not sure it's politically do-able.
I don't think he'd have the patience for the bs. He appears not to suffer fools lightly.
Here's a fun thing to imagine. There's another vacancy on the Supreme Court. Bush nominates Bolten. Leahy and Kennedy start grandstanding and Bolton slaps the bleep out of them. Ah, I can dream can't I?