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To: neverdem
"Among the antibacterial-related drivers of resistance, the inappropriate and excessive use of antibacterials has been identified."

Above from your link: "Excessive use" is NOT the same as a single long course of treatment.

As I said, I don't see how a continuous LONGER single use term of antibiotics can possibly cause antibiotic resistance compared to a SHORT single use term. I can easily understand how the reverse is possible, though.

And with Azithromycin, don't let the doctor stick you with the "three-day" course. It is NOT as effective as the "five-day" course.

19 posted on 06/10/2006 5:08:45 PM PDT by Wonder Warthog (The Hog of Steel-NRA)
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To: Wonder Warthog
As I said, I don't see how a continuous LONGER single use term of antibiotics can possibly cause antibiotic resistance compared to a SHORT single use term. I can easily understand how the reverse is possible, though.

"The development of resistance may be reduced by avoiding subtherapeutic antibacterial exposure and prolonged treatment durations."

There was a reason that I used that sentence from that abstract to make the link in comment # 17.

These bugs are acquiring resistance all the time through spontaneous mutations, plasmid acquired genes, etc. especially under prolonged treatment whether it's from monthlong courses for bacterial endocarditis, osteomyelitis, really prolonged acne treatment or controversial Lyme disease recommendations. Thanks for the tip about azithromycin, but I can write my own scripts.

22 posted on 06/10/2006 10:08:23 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
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