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Stem cells regrow damaged nerves in rats: US study
Reuters - Science ^ | 2006-06-20

Posted on 6/20/2006, 9:31:24 PM by Junior

WASHINGTON (Reuters) - Stem cells taken from mouse embryos have helped paralyzed rats move again, U.S. researchers said on Monday.

The study was the best evidence so far that controversial embryonic stem cells might be used to treat people with spinal cord and other traumatic injuries, the researchers said.

"This study provides a 'recipe' for using stem cells to reconnect the nervous system," Dr. Douglas Kerr of The Johns Hopkins University School of Medicine said in a statement.

"It raises the notion that we can eventually achieve this in humans, although we have a long way to go ... We found that we needed a combination of all of the treatments in order to restore function."

Kerr and colleagues used a soup of compounds called growth factors to cause stem cells from the mouse embryos to develop into a type of nerve cell called a motor neuron.

Writing in the Annals of Neurology, they said the transplanted cells, combined with the right mix of compounds, helped paralyzed rats regrow some of their nerve cells and use their hind legs.

"This work is a remarkable advance that can help us understand how stem cells might be used to treat injuries and disease and begin to fulfill their great promise," said Dr. Elias Zerhouni, director of the National Institutes of Health, which funded the study.

Stem cells are the body's master cells and can be found circulating in the blood and in tissues. Scientists hope to learn to use them to regenerate cells, organs and tissues.

A controversial source of the stem cells comes from days-old embryos. These stem cells have the ability to change into any type of cell or tissue in the body.

Opponents of their use say experimenting on human embryos is morally wrong, and U.S. law prevents the use of federal funds to create or work with all but a few batches of human embryonic stem cells.

 


TOPICS: Culture/Society
KEYWORDS: stemcell
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1 posted on 6/20/2006, 9:31:26 PM by Junior
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To: Junior
"...damaged nerves in rats" Liberals have damaged nerves? Imagine that.
2 posted on 6/20/2006, 9:35:21 PM by Eagles Talon IV
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To: Junior

Michael Savage was talking about this a few months ago. Like myself, he preferred his rats dead. :)


3 posted on 6/20/2006, 9:35:24 PM by P-40 (Al Qaeda was working in Iraq. They were just undocumented.)
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To: Junior

I want some new stem cells. I want to feel young again. We have 'found" Pnce de Leons "Fountain of Youth" and I am sure their are no sideaffects /moralissues /fearofgeneticharm /unintendedconsequences /somethingdreadfulwecanteventhinkof /wrathofGodformessingaroundwiththingsweshouldnt /doriangrayissues


4 posted on 6/20/2006, 9:37:33 PM by BipolarBob (Yes I backed over the vampire, but I swear I looked in my rearview mirror.)
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To: Junior

Good news for democRats.


5 posted on 6/20/2006, 10:06:03 PM by boomop1 (there you go again)
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To: Junior
Stem cells taken from mouse embryos have helped paralyzed rats move again

Still no reason for the State of California to take my money and have me help pay for this research.

6 posted on 6/20/2006, 10:21:56 PM by Michael.SF. ("I don't think Pat Kennedy is crazy, he's just a drunk" -- G. Gordon Liddy (5-10-06))
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To: Junior
There have to have been some experiments that went wrong and some horrible after effects that we never hear about.
7 posted on 6/20/2006, 10:36:19 PM by mountainlyons (Hard core conservative)
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To: mountainlyons

"There have to have been some experiments that went wrong and some horrible after effects that we never hear about."

Such as the super-intelligent Uber Rats that have taken control of the basement of the lab...


8 posted on 6/20/2006, 10:52:26 PM by Army Air Corps (Four fried chickens and a coke)
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To: Army Air Corps

9 posted on 6/21/2006, 1:00:52 AM by Junior (Identical fecal matter, alternate diurnal period)
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To: Army Air Corps

10 posted on 6/21/2006, 1:00:52 AM by Junior (Identical fecal matter, alternate diurnal period)
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To: Michael.SF.

Do you think the government should pay for any research? Or should it only pay for research of which you approve?


11 posted on 6/21/2006, 1:03:12 AM by Junior (Identical fecal matter, alternate diurnal period)
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To: Junior
Or should it only pay for research of which you approve?

I think I should have veto authority on all government expenditures. We would all be better for it.

;)

12 posted on 6/21/2006, 1:07:01 AM by Michael.SF. ("I don't think Pat Kennedy is crazy, he's just a drunk" -- G. Gordon Liddy (5-10-06))
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To: Junior

Stem cells from a different species cured nerve damage ?

Why did the experiment not use "rat stem cells" to cure rat nerve damage ?

Why not use the rat's own stem cells so that the DNA of living cells is fully compatible with the animal's immune system ?


13 posted on 6/21/2006, 1:10:22 AM by JustDoItAlways
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To: Junior
Seriously, certainly certain research is warranted in many areas. But note that I said "state" not "federal".

California is dominated by a democrat legislature and has passed a referendum obligating us to pay for questionable research. I think that is a misuse of state funds, based on liberal dogma and feelings.

If private funds want to support this research, then fine, but not state. I am also oppossed to federal funds being spent on this research, but feel that there are better checks and balances in place on the national level then there are on the local state level.

14 posted on 6/21/2006, 1:14:20 AM by Michael.SF. ("I don't think Pat Kennedy is crazy, he's just a drunk" -- G. Gordon Liddy (5-10-06))
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To: Junior

Narf!


15 posted on 6/21/2006, 1:19:36 AM by Army Air Corps (Four fried chickens and a coke)
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To: Michael.SF.

How is this "questionable" research? The results most definitely indicate otherwise.


16 posted on 6/21/2006, 11:21:44 AM by Junior (Identical fecal matter, alternate diurnal period)
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To: Junior
Perhaps "questionable" was the wrong word to use. I should have said: "Research which is strongly objected to by some segments of sciety based on moral grounds"

again, my objections are not on the research itself, but on the use of government funds for this research. There are or should be plenty of private funds available for this research.

17 posted on 6/21/2006, 1:14:26 PM by Michael.SF. ("I don't think Pat Kennedy is crazy, he's just a drunk" -- G. Gordon Liddy (5-10-06))
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To: Eagles Talon IV

Damaged may not mean severed hence the re-growth seen. Needs to be reproduced.


18 posted on 6/21/2006, 1:27:03 PM by revolted
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To: Junior

The chief concern with the use of embryonic stem cells is the development of cancer cells.

The report of this study seems to be incomplete. It does not present the long term effects of the use of embryonic stem cells in these rats. Nor does it note whether or not adult stem cells can accomplish the same nerve damage repair.

Always question the motives of Reuters. The information that is missing from a Reuters article is just as important as what is presented.


19 posted on 6/21/2006, 1:35:14 PM by kidd (If God is your co-pilot, try switching seats)
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To: Junior
Stem cells are the body's master cells and can be found circulating in the blood and in tissues. Scientists hope to learn to use them to regenerate cells, organs and tissues.

A controversial source of the stem cells comes from days-old embryos. These stem cells have the ability to change into any type of cell or tissue in the body.

The author of the article either accidentally or purposely conflates the types of stem cells ... the stem cells that 'can be found circulating in the blood and tissue' are not embryonic stem cells, but the author dissembles the text in such a way as to imply they are. ONLY at embryo age in the human lifetime are the 'body's master cells' called embryonic stem cells (totipotent, meaning able to trun into all the organs and tissues of the body); in older humans, the stem cells are no longer totipotent, rather they have differentiated into pluripotency, then multipotency, to become the master cells building specific tissues and organs. The 'master cells circulating in blood and tissue' are sometimes called MAPCs, for multipotent adult progenitor cells.

20 posted on 6/21/2006, 1:46:41 PM by MHGinTN (If you can read this, you've had life support from someone. Promote life support for others.)
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