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To: oblomov

Where do you get it? I take meds that prohibit the use of alcohol.


22 posted on 11/01/2006 5:20:18 PM PST by From many - one.
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To: From many - one.

Sonmeone emailed me with a similar question, and also asked where he could get more information. Here was my reply:

Hello,

First, let me point out that I only take a small dose daily compared to the researcher (Dr. Sinclair, who still claimed to take something on the order of 5mg/kg body weight, which would be 375 mg daily for a 75kg person. That would be quite expensive based on the resveratrol prices I have been able to find.) Functional food-based nutrients are regarded as having the best bioavailability, and if you look at the articles below, you'll see that the amount found in ordinary servings of food (like wine and peanut butter) is quite low. But I expect food-based resveratrol to be marketed very soon. The experts seem to favor resveratrol that is derived from grapeskin extract (which has the highest concentration of any food). Generally the LEF and Jarrow products are quite good in terms of bioavailability.

There is a lot of good information on resveratrol (and other antioxidants) here:

http://search.lef.org/cgi-src-bin/MsmGo.exe?grab_id=0&page_id=885&query=Resveratrol&hiword=RESVERATROLA%20RESVERATROLS%20Resveratrol%20

LEF is a commercial site, and you can buy the products there- the dosage per pill for their product is 20 mg (I take this one).

I have also taken the Jarrow resveratrol:
http://www.vitacost.com/Jarrow-Formulas-Resveratrol-Synergy

This article is a good basic resource on gene silencing (includes refs to resveratrol):
http://www.benbest.com/lifeext/aging.html#silencing

Linus Pauling Institute on resveratrol:
http://lpi.oregonstate.edu/infocenter/phytochemicals/resveratrol/

PDR:
http://pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/res_0224.shtml

A somewhat skeptical view:
http://www.quackwatch.org/01QuackeryRelatedTopics/DSH/resveratrol.html

Note: I'm not a doctor-just an interested layman. I don't think that researchers yet understand potential interactions with certain health conditions, medicines, etc. so it would probably be smart to discuss with your doctor.

My best,
oblomov


24 posted on 11/01/2006 8:00:39 PM PST by oblomov (Join the FR Folding@Home Team (#36120) keyword: folding@home)
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