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Small molecule offers hope for cancer treatment
CTV.CA ^ | 1/17/06 | Staff

Posted on 01/17/2007 6:33:23 AM PST by Michael_Michaelangelo

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To: spunkets

Good grief, how did you ever get that from allowing people to get freely what are now resticted to prescription access?

How is that more rather than less nanny-statism?


The only restrictons I would apply are to those few antibiotics that must be reserved for use against rapidly evolving bacteria.


61 posted on 01/17/2007 12:05:34 PM PST by From many - one.
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To: redgolum

Read my post carefully..I would restrict the newer antibiotics. That as my only exception.


62 posted on 01/17/2007 12:08:05 PM PST by From many - one.
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To: spunkets

"..It's really a concern to maintain and further the professional monopoly. It's an income thing and a jobs program for ninnies."

Not really. It is more nanny-statism. Most patients would still see their physician to get recomendations.

Some meds are dangerous if mis-used, but so are automobiles.


63 posted on 01/17/2007 12:14:50 PM PST by From many - one.
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To: From many - one.
"How is that more rather than less nanny-statism? "

I didn't say it was more. I just pointed out the foundational motivation for fedgov to do any of this type of control. It denies the rights of all according to the lowest common denominator.

"The only restrictons I would apply are to those few antibiotics that must be reserved for use against rapidly evolving bacteria."

That applies to them all. Ever note the "alarming" news stories of drugs findings in water treatment plant effluent? In general, the concern only applies to high densities of sick people and high densities of pathogens. It is bad to use antibiotics in cases where they are not warranted. The antis you're alluding to are not generally appropriate for most infections anyway. The prescription scheme presumes, then establishes by fiat, that only certain folks have the ability to know, understand and use the materials involved. That is not the case. It is not all that hard to determine that a disease needs an antibiotic to facilitate a cure, which one applies and then read the directions.

"It is more nanny-statism. Most patients would still see their physician to get recomendations."

It's true that they would and most should, but their fundamental motive in law making is to protect the monopoly. It began ~1840 when the docs forming the AMA realized that they needed to do something about intelligent folks treating themselves successfully. They needed to put an end to that, because they were cutting into their bottom lines.

64 posted on 01/17/2007 1:05:14 PM PST by spunkets
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To: spunkets

Antibiotic usage is more of an issue than you seem to recognize.

Just to clarify for me: do we agree that the fewest possible substances be restricted? And further that the restrictions, if any, should be a public health matter only, not a livlihood protection?

If we agree there, then we have a common base to hash out antibiotics. If not, then agreeing to disagree might be best


65 posted on 01/17/2007 2:01:58 PM PST by From many - one.
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To: A. Pole; Mase
Press here if you would like to learn a thing or two.
66 posted on 01/17/2007 6:05:16 PM PST by Pharmboy ([She turned me into a] Newt! in '08)
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To: Michael_Michaelangelo

There are some amazing things going on now in biochemistry.

Two of the brightest stars on the horizon are Alpha Lipoic acid and Acetyl-L-Carnitine, both of which have to do with mitochondrial functioning.

Animals given doses of the above end up recycling alot of their Vitamin C and have much elevated antioxidant levels in their cells. Their mitochondria get positively perky!


67 posted on 01/17/2007 6:10:12 PM PST by djf (Democracy - n, def: The group that gets PAID THE MOST ends up VOTING THE MOST See: TRAGEDY)
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To: Michael_Michaelangelo

bttt


68 posted on 01/18/2007 12:55:28 AM PST by TigersEye (If you don't understand the 2nd Amendment you don't understand America.)
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To: Mase
Of course Nexium worked better, it's twice the strength 40mg vs 20mg. I agree totally that we have the best medicine and that the FDA is a real pain. However, if you were to study the history of drugs/drug companies & the FDA you would find that every time the FDA has loosened regs the drugs companies have done somethings deceitful which caused even stricter regs. You want to know why you can buy drugs cheaper in Canada? Because US drugs companies sell them to Canada much cheaper than the do here. Why??????? Shouldn't those R&D cost be passed along to everyone who benefits & not just the American public?
I see both sides, no need for anger. I am truly glad the pharmacuetical industry, which I am proud to be a part of, has lenghtened your lifespan.
69 posted on 01/18/2007 12:51:37 PM PST by millerph
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To: MJemison
I don't know, but since they came out with Prevacid Solutabs and many insurances now cover the Solutabs, but not the capsules it is an indication it won't be too long. They give rebate to the insurance companies for the Solutabs, quit detailing the caps to doctors & tell them how much better the Solutabs work so they will start writing for them. They probably got a patent extension for the Solutabs because it's a different dosage form. My guess, capsules will go generic in less than a year.
70 posted on 01/18/2007 12:57:20 PM PST by millerph
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To: millerph
I don't know, but since they came out with Prevacid Solutabs and many insurances now cover the Solutabs, but not the capsules it is an indication it won't be too long. They give rebate to the insurance companies for the Solutabs, quit detailing the caps to doctors & tell them how much better the Solutabs work so they will start writing for them. They probably got a patent extension for the Solutabs because it's a different dosage form. My guess, capsules will go generic in less than a year.

Many Thanks! Trying to get this info from the doctors and insurance companies is like pulling teeth. It seems Freepers are better-informed than either of them. Since our insurance didn't cover non-generics, we were in a bind (hubby can't tolerate the other meds mentioned).

71 posted on 01/18/2007 1:31:35 PM PST by MJemison
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To: millerph
Of course Nexium worked better, it's twice the strength 40mg vs 20mg

By intentionally picking only the S conformation the drug becomes more potent. I don't care if its efficacy is only marginally improved, the benefits are very real. In many cases these so called "me too" drugs can be made more effective, and with lesser side effects, by removing the D component entirely.

Also,Prilosec OTC isn’t the same as Prilosec. They’re both omeprazole, but the salt is different. OTC is omeprazole magnesium, whereas the prescription product is omprazole sodium. OTC is supposed to be for short-term use only but I've not seen anything proving it. Some have suggested that OTC could be unhealthy if used long-term. If someone is going to use Prilosec for the long term it's better to have a prescription.

However, if you were to study the history of drugs/drug companies & the FDA you would find that every time the FDA has loosened regs the drugs companies have done somethings deceitful which caused even stricter regs.

If you understand the FDA you know that they're driven by politics, public opinion and covering their ass. Not long ago there was public outcry that the FDA was sitting on therapies that could help people suffering from from specific diseases. In response, the FDA began fast tracking drugs. Then the problem with Vioxx occurred so the FDA reacted by playing it slow once again.

You want to know why you can buy drugs cheaper in Canada?

Because Canada dictates what prices the pharmaceutical makers can charge for their products. The Canadian government is the only entity that can purchase drugs in Canada.

Because US drugs companies sell them to Canada much cheaper than the do here.

Unfortunately, they're not given a choice. They either sell them for what the Canadian government is willing to pay or they don't get to sell them at all. At least the drug makers can use the volume to help cover their significant manufacturing overhead. If the manufacturer refuses to sell at the price the Canadian government is willing to pay, the Canadian government will threaten to ignore their patents and allow their generic industry to copy the drugs. Here's and easy question: name all the innovative drugs Canada has created over the last 25 years. Countries who practice price controls don't create new drugs.

Shouldn't those R&D cost be passed along to everyone who benefits & not just the American public?

Yes, they should. But you can thank the foreign socialists who, once again, leech off the U.S for this sad state of affairs. If this country ever adopts price controls you can kiss innovation goodbye and all the world will suffer.

72 posted on 01/18/2007 3:25:13 PM PST by Mase (Save me from the people who would save me from myself!)
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To: Pharmboy

Thanks for that study. I'm looking forward to reading it over the weekend. After brushing over it I can tell this is the kind of information that should be required reading for all students. It would temper the enthusiasm of many who believe we can innovate by controlling drug company prices and profits.


73 posted on 01/18/2007 3:30:16 PM PST by Mase (Save me from the people who would save me from myself!)
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To: Michael_Michaelangelo

bump


74 posted on 01/18/2007 3:32:07 PM PST by VOA
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To: FairWitness; mtbopfuyn

Hey mtbobfuyn,
Fairwitness has a great idea. Why don't all those terrific generic companies take the massive profits they make and actually do something that benefits patients?! Better yet, why don't you start up a company that supplies this new drug to the world. You seem like a truly altruistic individual who cares nothing about making profits for your company or its investors. Go ahead! Give it a go!...
No? I didn't think so. Unless you are prepared to do the homework to understand the industry, it might be a good idea to keep your trap shut.


75 posted on 01/18/2007 3:36:54 PM PST by go-dubya-04
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To: Mase; A. Pole
Mase,
It is more than obvious that A. Pole is really just an A. Hole. Someone so steeped in their bitter ideology that facts will never sway them. I love these "conservatives" who want to drag down pharmaceutical companies as desperately as the most radical Marxist. You cannot reason with them so don't waste your time with buffoons like this.
76 posted on 01/18/2007 3:45:18 PM PST by go-dubya-04
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To: go-dubya-04
Someone so steeped in their bitter ideology that facts will never sway them.

As it is said, you can take the boy out of communism but you can't take communism out of the boy.

77 posted on 01/19/2007 6:54:15 AM PST by Mase (Save me from the people who would save me from myself!)
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To: All
If you would like up-to-date information on any plans for clinical trials of DCA in patients with cancer, or would like to donate towards a fund for such trials, please visit the site set up by the University of Alberta and the Alberta Cancer Board.

DCA RESEARCH INFORMATION

78 posted on 02/01/2007 12:25:29 PM PST by Michael_Michaelangelo (The best theory is not ipso facto a good theory.)
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