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Scientists Isolate Chemical In Curry That May Help Immune System Clear Plaques Found In Alzheimer's
Science Daily ^ | 2-17-2007 | University Of California

Posted on 07/17/2007 5:06:43 PM PDT by blam

Source: University of California - Los Angeles
Date: July 17, 2007

Scientists Isolate Chemical In Curry That May Help Immune System Clear Plaques Found In Alzheimer's

Science Daily — Researchers have isolated bisdemethoxycurcumin, the active ingredient of curcuminoids -- a natural substance found in turmeric root -- that may help boost the immune system in clearing amyloid beta, a peptide that forms the plaques found in Alzheimer's disease. Using blood samples from Alzheimer's disease patients, researchers found that bisdemethoxycurcumin boosted immune cells called macrophages to clear amyloid beta.

Ground turmeric in small bowl. (Credit: iStockphoto/Jenny Horne)

In addition, researchers identified the immune genes associated with this activity.

The study provides more insight into the role of the immune system in Alzheimer's disease and points to a new treatment approach. Researchers say that it may be possible to test a patient's immune response with a blood sample in order to individualize treatment. The genes involved in the process, called MGAT III and Toll-like receptors, are also responsible for a number of other key functions in the immune system.

The results also suggest a new drug development approach for the disease that differs from the amyloid-beta vaccine. The new approach relies on the innate immune system, which is present at birth rather than on antibodies produced by B cells, which is a later developed part of the active immune system.

Authors of the study include Dr. Milan Fiala, a researcher with the David Geffen School of Medicine and the VA Greater Los Angeles Health Care System and Dr. John Cashman, director of the Human BioMolecular Research Institute (HBRI) in San Diego.

Cashman received study funding from the Alzheimer's Drug Discovery Foundation and Fiala from the Alzheimer's Disease Association.

The research appears in the July 16 early edition of the Proceedings of the National Academy of Sciences.

Note: This story has been adapted from a news release issued by University of California - Los Angeles.


TOPICS: News/Current Events
KEYWORDS: alzheimer; curcumin; curry; health; mentalhealth; nutrition; plaques; scientists; supplements; tumeric
I've read that curry is presently the most popular food in England.
1 posted on 07/17/2007 5:06:45 PM PDT by blam
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To: blam; neverdem

Curry is very popular in India and Pakistan also.
Had a niece that lived in Canada with a lot of Pakistans and India people in her apartment building, the smell would about knock you over, came right through the walls.


2 posted on 07/17/2007 5:18:12 PM PDT by sweetiepiezer (Boycott China)
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To: blam

I would believe that Hala certified food such as goat and camel would be more popular./s


3 posted on 07/17/2007 5:18:35 PM PDT by doc1019 (Fred Thompson '08)
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To: blam

Well, it’s not a food but you’re right. Curry is very popular and why not? British food for the most part sucks. I have a theory as to why the Brits conquered the world. They were in search of some good cooking. So far, no one has been able to refute it.


4 posted on 07/17/2007 5:22:35 PM PDT by saganite (Billions and billions and billions----and that's just the NASA budget!)
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To: doc1019

Halal


5 posted on 07/17/2007 5:23:39 PM PDT by saganite (Billions and billions and billions----and that's just the NASA budget!)
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To: saganite
Halal -------------------------------------- That is right and with England being 10% Muslin, it would be popular there. __________________________________________ Halal (حلال, ḥalāl, halaal) is an Arabic term meaning "permissible". In the English language it most frequently refers to food that is permissible according to Islamic law. In the Arabic language it refers to anything that is permissible under Islam.
6 posted on 07/17/2007 5:27:09 PM PDT by sweetiepiezer (Boycott China)
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To: saganite

Thanks, I needed that. (oops). ;-)


7 posted on 07/17/2007 5:30:11 PM PDT by doc1019 (Fred Thompson '08)
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To: blam

Curcumin is very useful as an anti-inflammatory, and thus as an anti-cancer agent: http://www.lef.org/magazine/mag2002/jul2002_report_curcumin_01.html


8 posted on 07/17/2007 5:30:12 PM PDT by Ancesthntr
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To: sweetiepiezer

Well to my knowlwdge curry has nothing to do with Halal food and I for one love it. Whenever I can get to a real Indian restaurant I order chicken curry. MMMM!


9 posted on 07/17/2007 5:31:02 PM PDT by saganite (Billions and billions and billions----and that's just the NASA budget!)
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To: blam
My dog has arthritis and give her one curcumin capsule a day.
10 posted on 07/17/2007 5:31:37 PM PDT by SamiGirl
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To: SLB

FYI


11 posted on 07/17/2007 5:37:04 PM PDT by Stonewall Jackson (The Hunt for FRed November. 11/04/08)
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To: SamiGirl
"My dog has arthritis and give her one curcumin capsule a day."

Can you give me a link to your drug/source? I have some old dogs.

12 posted on 07/17/2007 5:43:06 PM PDT by blam (Secure the border and enforce the law)
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To: blam
Reminds me of the 1960's Donovan song, "Mellow Yellow"....."I'm just wild about saffron...."

He marched on into obscurity, as did most of the "British Invasion" groups of that era.

13 posted on 07/17/2007 5:51:23 PM PDT by capt. norm (Be thankful we're not getting all the government we're paying for.)
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To: blam
Researchers have isolated bisdemethoxycurcumin, the active ingredient of curcuminoids -- a natural substance found in turmeric root -- that may help boost the immune system in clearing amyloid beta, a peptide that forms the plaques found in Alzheimer's disease.

Many prepared mustards also have turmeric, including the classic French's yellow mustard and Colman's prepared mustard. (I don't believe that some other prepared mustards such as Maille's Dijon Originale have any turmeric.)

14 posted on 07/17/2007 5:52:33 PM PDT by snowsislander
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To: sweetiepiezer
I love Indian food. I hate Altheimers. My Mother in law had it and we had her in our home for two years. It was two years that was not Hell, but it was bad.
15 posted on 07/17/2007 6:13:29 PM PDT by GeorgefromGeorgia
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To: blam

Hi Blam,

I buy curcumin at Whole Foods. It’s called Curcumin 95 and it’s made by Jarrow Formulas. It comes in a bottle of 60 capsules, 500 mg each. I give my dog one capsule each morning. She likes cheese, so I hide it in a slice of American cheese. I’ve only been doing this for about a month; it’s not a miracle, but it seems to help.

I also give her four baby aspirins/day (the coated ones).


16 posted on 07/17/2007 6:16:04 PM PDT by SamiGirl
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To: SamiGirl

Thanks.


17 posted on 07/17/2007 6:23:02 PM PDT by blam (Secure the border and enforce the law)
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To: saganite

http://www.geocities.jp/kobehalalfood/newpage1.htm


18 posted on 07/17/2007 6:25:42 PM PDT by sweetiepiezer (Boycott China)
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To: saganite

If you want a good meal in England, choose breakfast.


19 posted on 07/17/2007 7:00:38 PM PDT by Hilltop (?)
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To: blam
Good for Alzheimer's eh?

This one seems to clear out the sluices. I wish I could remember what it is called

20 posted on 07/17/2007 7:01:15 PM PDT by mylife (The Roar Of The Masses Could Be Farts)
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To: blam
I've read that curry is presently the most popular food in England.

I think it's been popular for a pretty long time. One of my parents was English and we ate curry frequently.

21 posted on 07/17/2007 7:12:14 PM PDT by wideminded
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To: Hilltop
If you want a good meal in England, choose breakfast

Or go to an Indian restaurant. However, in recent years the English have become more demanding of good food. Some of the combination pub and restaurants will serve a quit decent meal. Twenty years ago the food was appalling at best!

22 posted on 07/17/2007 8:53:11 PM PDT by cpdiii (Pharmacist, Pilot, Geologist, Oil Field Trash and proud of it.)
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To: SamiGirl

That is too much aspirin for any dog!


23 posted on 07/17/2007 8:58:20 PM PDT by Doctor Don
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To: Doctor Don

I appreciate your reply. She’s a big dog (german shepherd). These are baby aspirins. The vet recommended it, but now you got me thinking ...


24 posted on 07/17/2007 9:33:21 PM PDT by SamiGirl
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To: blam

Here is another article concerning research into Alzheimer’s Disease.

Scientists ‘step closer to Alzheimer’s cure’

http://www.freerepublic.com/focus/news/1870256/posts


25 posted on 07/23/2007 8:16:30 AM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimer's!)
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To: DixieOklahoma; reuben barruchstein; theprophetyellszambolamboromo; Alusch; house of cards; ...

.


26 posted on 07/24/2007 9:20:11 PM PDT by Coleus (Pro Deo et Patria)
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