Yep. If you look at the trends shown in ice core data it appears that we are headed for another ice age, although certainly not in my lifetime. These cycles have been going on EONS before humans ever walked the planet. No one fully understands them because they are so complex. For the same reason climate models don't begin to tell the whole picture. Thus, meteorologists and climatologists cannot begin to accurately predict the future, despite how much some of them want you to think they can.
There really isn't really anything humans can do to stop or alter these cycles. So, those species that adapt will survive. Those that don't, won't.