Are you suggesting that there are even infrequent AEs of serotonin syndrome which are caused by SSRIs? That would be big news. You casually and causally link them implicitly in your imperative statement. There is no such causal link which has been established to my knowledge. Further, the occurence of serotonin sydrome (even in patients taking SSRIs) is not so much as to even make the RARE (less than 1 in 1000) AEs for Prozac, Zoloft and Celexa (the first three I looked at the PIs for).
You can't make the diagnosis if you don't know it exists. I saw a patient in the hospital on multiple antidepressants complaining of palpitations with an abnormaly fast heart rate, a supraventricular tachycardia. I didn't know about serotonin sydrome at the time, but I could check with the pharmacy and find that a number of her meds can cause tachycardia. I called her shrink who insisted that the patient had to remain on her meds even though she was symptomatic.
A Mix of Medicines That Can Be Lethal my thread
A Mix of Medicines That Can Be Lethal the NY Times printer friendly version
The Serotonin Syndrome pdf link to the NEJM article
The incidence of the serotonin syndrome is thought to mirror the increasing number of proserotonergic agents being used in clinical practice. 7 In 2002, the Toxic Exposure Surveillance System, which receives case descriptions from office-based practices, inpatient settings, and emergency departments, reported 26,733 incidences of exposure to selective serotonin-reuptake inhibitors (SSRIs) that caused significant toxic effects in 7349 persons and resulted in 93 deaths. 8,9 The assessment of the serotonin syndrome in therapeutic drug dosing has relied on post-marketing surveillance studies, one of which identified an incidence of 0.4 case per 1000 patient-months for patients who were taking nefazodone. 10 Performing a rigorous epidemiologic assessment of the serotonin syndrome, however, is difficult, since more than 85 percent of physicians are unaware of the serotonin syndrome as a clinical diagnosis. 10 The syndrome occurs in approximately 14 to 16 percent of persons who overdose on SSRIs. 8