As we never will know any system in full, the best approach for most practical reasons is to assume randomness - and let the philosophers quibble about the difference between randomness and unpredictability....
However, the term "random" is rooted in mathematics. The issue is not a "quibble" of philosophy, it is a matter of "proof" and accuracy in speaking.
If one pointed to a rectangle with four right angels and parallel, equal sides and declared it a "trapezoid" we'd say "Not so fast, it is a square, a trapezoid has only two sides parallel and it does not have four right angles."
Likewise, if one points to a thing and says to me it is "random" I'll reply "If you have established a uniform distribution, then perhaps so, but only to the extent of your measurement - because you cannot say something is random in the system unless you know what the system 'is.'"