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The Claim: Identical Twins Have Identical DNA (No, copy-number variation strikes again!)
NY Times ^ | March 11, 2008 | ANAHAD O’CONNOR

Posted on 03/15/2008 12:24:17 AM PDT by neverdem

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To: sageb1

“A few years ago in Dunwich a half-witted girl bore illegitimate twins. One of them was almost human.

-—H. P. Lovecraft


21 posted on 03/15/2008 8:41:05 AM PDT by Mike Darancette (Democrat Happens!)
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To: allmendream; martin_fierro; Charles Henrickson
The DNA sequence is identical, but they end up getting methylated at different positions

Which brings up the thought that, if you think you see identical twins at a bar, you've probably had too much...

22 posted on 03/15/2008 10:00:57 AM PDT by mikrofon (Give me a Double)
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To: Straight Vermonter
Epigenetics is going to be the next great field in medicine.

Epigenetics is one thing. Copy number variation is quite another. It includes a range in the number of copies of a gene, from deletion, i.e. the absense of the gene altogether, to multiple copies of the same gene to different versions of a gene that makes a different, but functionally similar, protein, e.g. pancreatic amylase and salivary amylase. Click on the keywords copynumbervariation, copynumbervariations and cnv. It's not just simple Mendelian genetics and epigenetics.

23 posted on 03/15/2008 10:37:22 AM PDT by neverdem
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To: Leftism is Mentally Deranged
What the article says is the they DO have identical DNA, but that changes can develop soon after fertilization. Another case of the headline being written by an brain-deficient moron.

No, check the link in comment# 1 and the keywords copynumbervariation, copynumbervariations and cnv. In the case of twins, copy-number variation means that the twins can have zero to multiple copies of the same gene.

24 posted on 03/15/2008 10:54:48 AM PDT by neverdem
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
How epigenetics integrates nuclear functions

It's unrelated to the main theme underlying this thread, copy number variations, but since epigenetics was mentioned so often, I managed to come across this review article from a conference in 2005. It's fascinating, even if it may be already out of date.

25 posted on 03/15/2008 11:58:10 AM PDT by neverdem
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To: mikrofon
Unless they happen to be the O'Malley's
26 posted on 03/15/2008 2:23:39 PM PDT by mikrofon (Happy St. Paddy's Day)
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To: Does so

Not surprised: twins have different fingerprints.
....and fingerprints are not the result of genes?


27 posted on 04/09/2008 2:00:10 AM PDT by Bellflower (A Brand New Day Is Coming!)
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To: Bellflower
....and fingerprints are not the result of genes?

The article says, "identical, they are not". My recollection is that fingerprints aren't programmed like genes. They "just grow".

Monkeys have fingerprints, too, BTW. (And suspect they are not alike in monkey-twins as well—though I haven't checked!)

:)

28 posted on 04/09/2008 3:21:55 AM PDT by Does so (...against all enemies, DOMESTIC and foreign...)
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