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Regrowing Limbs: Can People Regenerate Body Parts?
sciam ^ | April, 2008 | By Ken Muneoka, Manjong Han and David M. Gardiner

Posted on 03/18/2008 6:47:11 PM PDT by Flavius

Progress on the road to regenerating major body parts, salamander-style, could transform the treatment of amputations and major wounds

* The gold standard for limb regeneration is the salamander, which can grow perfect replacements for lost body parts throughout its lifetime. Understanding how can provide a road map for human limb regeneration. * The early responses of tissues at an amputation site are not that different in salamanders and in humans, but eventually human tissues form a scar, whereas the salamander’s reactivate an embryonic development program to build a new limb. * Learning to control the human wound environment to trigger salamanderlike healing could make it possible to regenerate large body parts.

A salamander’s limbs are smaller and a bit slimier than those of most people, but otherwise they are not that different from their human counterparts. The salamander limb is encased in skin, and inside it is composed of a bony skeleton, muscles, ligaments, tendons, nerves and blood vessels. A loose arrangement of cells called fibroblasts holds all these internal tissues together and gives the limb its shape.

(Excerpt) Read more at sciam.com ...


TOPICS: News/Current Events
KEYWORDS: body; health; medicine; regeneration

1 posted on 03/18/2008 6:47:12 PM PDT by Flavius
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To: Flavius

I lost a fingernail once, from the cuticle to the tip, and it completely regenerated itself. Does that count as a limb?


2 posted on 03/18/2008 6:48:43 PM PDT by highimpact (Abortion - [n]: human sacrifice at the altar of convenience.)
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To: Flavius

Hasn’t Paul McCartney had a rough enough week already?


3 posted on 03/18/2008 6:49:40 PM PDT by jdm ("You only live once and usually not even then." - Michael O'Donoghue)
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To: Flavius

Paging Heather Mills!


4 posted on 03/18/2008 6:50:55 PM PDT by Revolting cat! ("I am like...Dude......do you really....like want the Sex?")
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To: Flavius
Well, Obama is trying to move the foot that keeps regenerating out of his mouth.
5 posted on 03/18/2008 6:52:10 PM PDT by A CA Guy ( God Bless America, God bless and keep safe our fighting men and women.)
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To: Flavius; neverdem

BTTT


6 posted on 03/18/2008 6:53:11 PM PDT by Fiddlstix (Warning! This Is A Subliminal Tagline! Read it at your own risk!(Presented by TagLines R US))
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To: Flavius

Does it grow any GOP leadership spines?


7 posted on 03/18/2008 6:56:08 PM PDT by tflabo (Truth or tyranny)
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To: highimpact

The same thing happened to me. The doctor told me humans can regenerate fingertips indefinitely so long as the amputation does not extend beyond the tip of the fingerbone. It was fascinating to watch my fingertip regrow layer by layer (including the fingerprint) over the few months it took to regenerate.


8 posted on 03/18/2008 6:56:47 PM PDT by B-Chan (Catholic. Monarchist. Texan. Any questions?)
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To: Fiddlstix

thanks, bfl


9 posted on 03/18/2008 6:58:05 PM PDT by neverdem
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To: highimpact
this technology could quickly get outa hand
10 posted on 03/18/2008 7:00:23 PM PDT by Selmore (Pay no attention to that man behind the curtain.)
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To: Flavius

Placeholder ping


11 posted on 03/18/2008 7:02:12 PM PDT by Ignatz (I gave up self-sacrifice for Lent.)
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To: A CA Guy

HA!


12 posted on 03/18/2008 7:03:16 PM PDT by Lizavetta
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To: Flavius

Ah, interesting news to all of us who read A Wrinkle in Time as children.


13 posted on 03/18/2008 7:04:06 PM PDT by conservative cat
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To: Selmore

If it costs an arm and a leg to regrow an arm, then are you really better off?


14 posted on 03/18/2008 7:04:43 PM PDT by who_would_fardels_bear
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To: highimpact

Good for you! Not everyone’s fingertips will come back. Maybe you should let the nice doctors prod and poke ya a bit. (I wouldn’t, though.)


15 posted on 03/18/2008 7:06:06 PM PDT by Secret Agent Man
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To: All

not sure who this guy is

http://www.ted.com/talks/view/id/142


16 posted on 03/18/2008 7:07:02 PM PDT by Flavius (war gives peace its security)
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To: tflabo

good one!


17 posted on 03/18/2008 7:10:40 PM PDT by Siberian-psycho (An oppressed class which did not try to possess arms, would deserve to be treated as slaves." Lenin)
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To: jdm
LOL. Freepers are hot tonight!
18 posted on 03/18/2008 7:18:17 PM PDT by dhs12345
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To: Flavius

More importantly, a very rare phenomenon has been observed over the past several hundred years, of exclusively old men, who unexpectedly shed their teeth and regrew a completely new set.

This does not seem physiologically possible, as people are born with their adult teeth in development underneath their baby teeth. A dentist I mentioned this to postulated that they lived the bulk of their lives without the loss of their baby teeth, but this sounds just as unlikely.

But imagine what could be done for people with bad teeth, if their genetic trigger could be activated so that they would grow a new set of healthy teeth.

Imagine teething at the age of 40!


19 posted on 03/18/2008 7:18:53 PM PDT by yefragetuwrabrumuy
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To: Flavius
My spider-sense is tingling for some reason.

Curtis Connors was born in Coral Gables, Florida. He was a gifted surgeon who enlisted in the army and was sent off to war. He performed emergency battlefield surgery on wounded GIs, but his right arm was injured in a blast and had to be amputated. After his return to civilian life as a research technologist, he became obsessed with uncovering the secrets of reptilian limb regeneration and studied reptilian biology extensively. From his home in the Florida Everglades, he finally developed an experimental serum taken from reptilian DNA. He successfully regrew the missing limb of a rabbit and then, despite the warnings of his wife Martha, chose to test it on himself. Connors ingested the formula and his missing arm did indeed grow back. The formula had a horrible side effect; Connors was subsequently transformed into a reptilian humanoid monster

20 posted on 03/18/2008 7:19:42 PM PDT by Names Ash Housewares
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To: yefragetuwrabrumuy

well if they regrow all organs

thats perpetual life

also it reminds me of the story of Shepard in a desert fixing ears and such


21 posted on 03/18/2008 7:21:23 PM PDT by Flavius (war gives peace its security)
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To: Flavius

John Bobbit is investigating this great news as we speak.


22 posted on 03/18/2008 7:22:16 PM PDT by adorno
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To: Flavius

I cut the end of my thumb off in 1992.

It grew back.

[but then again, I *am* a salamander]......8:)


23 posted on 03/18/2008 7:22:47 PM PDT by Salamander (And don't forget my Dog; fixed and consequent......)
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To: adorno

that video i posted is very good you should look at it


24 posted on 03/18/2008 7:23:44 PM PDT by Flavius (war gives peace its security)
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To: Flavius

Paging Jim Bobbitt. Jim Bobbitt, please pick up the white courtesy phone.


25 posted on 03/18/2008 7:36:40 PM PDT by austinaero
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To: conservative cat

OMG! “A Wrinkle in Time as children.”

I was one of those kids and that book made a huge impression on me at the time. We had to read it in 4th grade. I haven’t heard it mentioned in ages (and I mean AGES)!


26 posted on 03/18/2008 7:37:48 PM PDT by austinaero
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To: Flavius
I saw a small-mouth bass regrow his tail once. It was six years ago. My (then) boyfriend, Matt, had caught the fish and was keeping it in a huge tank. It was very interactive, and would come make eye contact with us and snap at our fingers if we touched the glass.

One day we noticed Bass was getting some sort of cobwebby fungus, so Matt transferred him to a very small tank just for a few days for intensive medication. The fish would hover in his small tank and stare longingly back at the big tank.

One afternoon, Matt came home to find Bass on the floor. He'd jumped out the thin opening in the back of the tank where the florescent light had been removed. He seemed to have been trying to get back to his old tank. But he must have lain on the floor for a half hour. He was dried out, his eyes were black, his gills barely moving.

Matt scooped him up, put him back in the big tank, and started dragging him through the water, back and forth, by the mouth, like you'd do a shark to revive him. He did this for about a half hour. Finally Bass started breathing on his own, but he just sank to the floor of the tank and lay propped there like a zombie for days. His eyes were black and glassy, he didn't eat, didn't respond to anything... and his tail, which was thin, had dried out and simply fell off.

Gradually, however, Bass started to make a come back. After about a week he started swimming around again, slowly, kind of dazedly. Then he started eating again. His eyes gradually lightened to hazel again, and he became aware of us once more. And ever so slowly, his tail grew back, but much darker, almost black.

When he was completely recovered, we took him back to the lake where Matt had caught him. We sat the bucket in the water with him in it and added lake water a little at a time so the temperature change wouldn't shock him. Finally we tipped the bucket over, and Bass swam forward about three feet and stopped. Then another three feet. Then he gave a twitch of his new, dark tail, and shot off into the lake, out of sight. I hope he lived long and prospered.

27 posted on 03/18/2008 7:40:07 PM PDT by A_perfect_lady
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To: highimpact
I lost a fingernail once, from the cuticle to the tip, and it completely regenerated itself. Does that count as a limb?

No, you must have a tail but if you don't object to a nail growing out your rear, maybe.

28 posted on 03/18/2008 7:43:14 PM PDT by Mind-numbed Robot (Not all that needs to be done, needs to be done by the government.)
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To: Flavius

Paging John Bobbitt, please pick up the white courtesy phone, John Bobbitt ...


29 posted on 03/18/2008 7:44:54 PM PDT by webschooner
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To: B-Chan

Fascinating! Thanks!


30 posted on 03/18/2008 7:44:54 PM PDT by Mind-numbed Robot (Not all that needs to be done, needs to be done by the government.)
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To: Flavius

Related ping.
http://www.freerepublic.com/focus/f-news/1972048/posts


31 posted on 03/18/2008 7:49:25 PM PDT by BGHater ($2300 is the limit of your Free Speech.)
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To: Flavius
http://www.ted.com/talks/view/id/142

Wow.

32 posted on 03/18/2008 7:52:25 PM PDT by magellan
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To: Flavius

salamander bump


33 posted on 03/18/2008 8:22:21 PM PDT by Luigi Vasellini (What do you call 2 toddlers and some duct tape??........muslim body armor!!!!!!!)
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To: Flavius

I shaved my head one summer and in four months — voila ! I had a full of head of hair again. Hair follicles have amazing regenerative ability. One of these days I will have to cut off my head and see if I can grow a new one.


34 posted on 03/18/2008 8:33:48 PM PDT by libh8er
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To: Flavius

What about the fifth limb?


35 posted on 03/18/2008 8:39:46 PM PDT by aruanan
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To: highimpact

I did the same thing. Cut off the tip of my pointer finger making a salad with company over. I cut the entire end off, some of the finger nail and everything. I was screaming pretty good, lots of blood! Threw away the salad. Wrapped it up for a few weeks, then forgot about it. A year later the same friends were over again and we were laughing about what had happened, they looked at my finger and freaked out. It had completely grown back, I hadn’t really noticed as it was a really slow process but they couldn’t believe it.


36 posted on 03/18/2008 8:51:28 PM PDT by TriGirl (Lurking for 7 years!!!!!)
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To: yefragetuwrabrumuy

>Imagine teething at the age of 40!

Imagine all the dentists out of work!


37 posted on 03/18/2008 8:56:07 PM PDT by ROTB (Front Runner=rich guy who doesn't hate evil and strives to offend no one, & WILL SELL YOU OUT.)
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To: aruanan
The Outer Limits

The Sixth Finger
38 posted on 03/18/2008 9:11:00 PM PDT by StormEye
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To: Flavius

Bmfl, great thread!


39 posted on 03/18/2008 10:17:24 PM PDT by Titan Magroyne ("Shorn, dumb and bleating is no way to go through life, son." Yeah, close enough.)
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To: who_would_fardels_bear

I guess that depends - are you right or left handed....


40 posted on 03/18/2008 11:22:54 PM PDT by ASOC (I know I don't look like much, but I raised a US Marine!)
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To: A CA Guy

Well, Obama is trying to move the foot that keeps regenerating out of his mouth.

I think his pastor stuck it up his a$$ for safe keeping

41 posted on 03/19/2008 12:59:15 AM PDT by Sarajevo (You're just jealous because the voices only talk to me.)
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To: A_perfect_lady

you should have eaten him.
that would have been a better ending.


42 posted on 03/21/2008 9:28:53 AM PDT by Selmore (Pay no attention to that man behind the curtain.)
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To: Selmore

Nah, Bass was cool. He was like a pet.


43 posted on 03/23/2008 1:50:12 PM PDT by A_perfect_lady
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To: Flavius; Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ...

BUMP & a regenerative medicine ping


44 posted on 04/11/2008 1:46:40 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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mark


45 posted on 05/26/2008 2:50:14 PM PDT by Titan Magroyne ("Shorn, dumb and bleating is no way to go through life, son." Yeah, close enough.)
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