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Roll Up Your Sleeve: Hypertension vaccine passes early test
Science News ^ | Week of March 15, 2008 | Nathan Seppa

Posted on 03/24/2008 12:13:13 AM PDT by neverdem

A new vaccine lowers blood pressure in hypertensive people, a study shows. The finding breaks ground in a field dominated by drug therapy.

Surges in blood pressure make physical exertion possible, but chronically elevated pressure spells trouble. Scientists have entertained the idea of immunizing people against high blood pressure for decades, but it hasn't been easy. The only other vaccine to reach the testing stage in people failed to reduce blood pressure.

A vaccine may augment or offer an alternative to blood pressure medications, known to cause side effects.

Several compounds orchestrate blood pressure changes, including a small protein called angiotensin. When cleaved by an enzyme, angiotensin signals blood vessels to constrict, increasing pressure.

Researchers created the new vaccine by binding angiotensin to a harmless fragment of a virus. The protein "is then recognized by the immune system as a virus," says study coauthor Martin Bachmann, an immunologist at Cytos Biotechnology in Schlieren, Switzerland. The immune system makes antibodies against angiotensin and pulls it out of circulation.

Bachmann and his colleagues gave 48 people with mild-to-moderate high blood pressure three injections of the vaccine over 12 weeks. Some received higher doses than others. Another 24 volunteers received sham injections. All patients used devices that monitored their blood pressure regularly day and night.

Two weeks after the last shot, those getting a higher dose of vaccine averaged systolic (top number) blood pressure that was 9 points less than those getting the placebo shots, the researchers report in the March 8 Lancet. The diastolic (bottom number) reading dropped only 4 points, a difference that could reflect chance.

However, compared with the sham-injection group, participants getting the higher vaccine dose had reductions of 25 points for the systolic reading and 13 points for the diastolic during early morning, when their risk of stroke...

(Excerpt) Read more at sciencenews.org ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: health; highbloodpressure; hypertension; medicine
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1 posted on 03/24/2008 12:13:13 AM PDT by neverdem
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To: neverdem

I have chronic hypertension. Beta blockers do a fair job of keeping it down, but I wouldn’t mind getting a vaccination every seventeen weeks, if it would help stabilize things.


2 posted on 03/24/2008 12:54:20 AM PDT by pallis
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To: pallis

Don’t forget, though, the law of unintended consequences. You don’t know what kind of havoc something like those could wreak with your immune system.


3 posted on 03/24/2008 1:01:40 AM PDT by Mr Ramsbotham (Laws against sodomy are honored in the breech.)
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To: pallis

Eat more bananas (potassium) and/or take Olive Leaf Extract.

Seriously.


4 posted on 03/24/2008 1:02:17 AM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: mkjessup

I take potassium, but sugar in fruit or any other means is a no no. I’ll have to try the olive leaf extract.


5 posted on 03/24/2008 1:15:01 AM PDT by pallis
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To: mkjessup

Where does one get Olive Leaf Extract?


6 posted on 03/24/2008 1:18:44 AM PDT by BunnySlippers (Buy a Mac ...)
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To: pallis
If you want to lower your blood pressure stop listening to the news. The MSM and their liberal BS is enough to kill us all.
7 posted on 03/24/2008 1:20:19 AM PDT by ME-262 (Nancy Pelosi is known to the state of CA to render Viagra ineffective causing reproductive harm.)
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To: BunnySlippers
Where does one get Olive Leaf Extract?

From OLEEC, the Olive Leaf Extract Exporting Countries cartel. It's about $110 a barrel. Biodiesel?

8 posted on 03/24/2008 3:01:15 AM PDT by RoadKingSE (How do you know that the light at the end of the tunnel isn't a muzzle flash?)
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To: mkjessup
Can you provide a link with more information on that?

Much appreciated.

9 posted on 03/24/2008 3:09:07 AM PDT by DCPatriot ("It aint what you don't know that kills you. It's what you know that aint so" Theodore Sturgeon))
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To: pallis

Is the avoidance of fruit sugar because of diabetes?


10 posted on 03/24/2008 3:10:36 AM PDT by DCPatriot ("It aint what you don't know that kills you. It's what you know that aint so" Theodore Sturgeon))
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To: neverdem

Wasn’t a simialar scenario used in Will Smith’s “I Am Legend”?


11 posted on 03/24/2008 4:11:48 AM PDT by BuffaloJack
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To: mkjessup

Not to mention going on a “Zone” like diet. My mother had hypertension for years, and finally stumbled upon a doctor that told her to cut out white flour, increase lean proteins and veggie intake. She is now considered in the normal range.

I didn’t know that about Olive Leaf Extract for hypertension. I take it for colds and sinus infections and such. It works wonders for that!


12 posted on 03/24/2008 4:39:13 AM PDT by Aggie Mama
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To: neverdem; Gabz; Paleo Conservative; Politicalmom; MamaTexan
Oh great. Something else for the government to advise us, mandate for us, er.... blackmail us with.
13 posted on 03/24/2008 4:41:35 AM PDT by metmom (Welfare was never meant to be a career choice.)
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To: mkjessup

mr. mm went on a low sodium diet for his kidney stones and his blood pressure dropped right to normal. Potassium helps with sodium regulation.


14 posted on 03/24/2008 4:43:55 AM PDT by metmom (Welfare was never meant to be a career choice.)
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To: pallis

have had it since I was 16 - now 45 - Ive been on them all - they lower nothing but my flag pole


15 posted on 03/24/2008 5:09:22 AM PDT by Revelation 911
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To: neverdem

My doctor has learned not to even mention a new drug to me. Unless I can be shown the double blind study showing it to be both safe and effective, he knows it is not going in me. Why would I want to be part of the test?


16 posted on 03/24/2008 5:31:51 AM PDT by deuteronlmy232 (Still trying to learn the rules.)
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To: DCPatriot

I have been sending Pressur-Lo tabs that are based on Hawthorn berries with lots of other stuff in it to two nuns in Viet Nam who have hypertension, one pretty severely. Both have good results from it. The severe one has added a Zona Plus device, which I also sent, to the pills. In a couple of weeks I will find out how well that works.


17 posted on 03/24/2008 5:39:40 AM PDT by ThanhPhero (di hanh huong den La Vang)
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To: pallis; BunnySlippers; DCPatriot; Aggie Mama; metmom
G'Morning all ...

Sorry for the delay in answering, a typical Monday with everything going insane (typical for me, lol), first I have a couple of links the first one is:

http://www.ncbi.nlm.nih.gov/pubmed/12489249

and there is also:

http://www.mskcc.org/mskcc/html/69315.cfm

and there is:

http://www.newswithviews.com/Howenstine/james6.htm

Just to name three. Google will provide you plenty of material if you want to read extensively on it.

I started taking Olive Leaf Extract for a severe sinus infection years and years ago, and after having gone the antihistamine, nasal sprays, decongestant route with little or no relief, the O.L.E. cleaned my sinus out inside of 30 days and I breathe freely without complications today. I find also, that if I feel a cold coming on, if I load up on O.L.E., Vitamin C, Vitamin E + L-Lysine, that if the cold does get a grip on me, it doesn't last too long.

I get Olive Leaf Extract in the supplement section of my local grocery store and most health food shops carry it, some brands are a bit high-priced but I wouldn't pay more than $10 to $12 a bottle (500 mg per capsule, 90 per bottle).

What surprised me (after my sinus got cleaned up) was that my blood pressure was substantially lower, earlier in that year (2001), my BP was running roughly 140 over 95 or so, now it is consistently 130 over 80, or in that neighborhood.

I also cut way down on salt and sodium in my diet.

DCPatriot? You ought to be able to find O.L.E. in any Super Giant grocery store, I would be surprised if they didn't carry it.

As for dosing, I don't think you can go too wrong with 500 mg 3 times a day (empty stomach, before meals is how I took it), and you may notice that you actually feel worse before you feel better, as O.L.E. is a pretty powerful substance, it flushes all sorts of toxins and bad stuff out of your system, and what you may feel is what is called the 'Dieoff effect' (no you're not gonna die! lol) ... it's just that when your body is first being cleaned up by the O.L.E., there may be a lot of toxins and not-so-healthy things flowing out of your system, but you should also experience a noticable increase in energy too, as you just feel better without all that other crap hanging around in your body.

Damn, I ought to be selling this stuff! LOL

Hope this is useful, have a great day and week!

Best,

MKJ ;)
18 posted on 03/24/2008 6:37:23 AM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: DCPatriot

Yes. About eight years ago I had a colon resection, and while in the hospital the doctors put me on insulin, and told me I would have to stay on it. Well, I ruptured, ended up staying in the hospital for 30 days without eating, and miracle of miracles, my blood sugar went down to normal. I eventually modified my diet to the point that I am off all blood sugar medications, and my doctor tells me I am no longer diabetic.


19 posted on 03/24/2008 9:01:54 AM PDT by pallis
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To: DCPatriot

Yes. About eight years ago I had a colon resection, and while in the hospital the doctors put me on insulin, and told me I would have to stay on it. Well, I ruptured, ended up staying in the hospital for 30 days without eating, and miracle of miracles, my blood sugar went down to normal. I eventually modified my diet to the point that I am off all blood sugar medications, and my doctor tells me I am no longer diabetic.


20 posted on 03/24/2008 9:01:59 AM PDT by pallis
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To: mkjessup
Thanks a lot for all the info, mkjessup.

Recently (several months ago) diagnosed with diabetes2 and also have hypertension. Taking meds for both and lost 20 lbs...just by avoiding carbs and raw sugars, etc..

I will definitely look up the olive leaf extract...since the blood pressure is what bugs me most. (strokes run in family history)

Be well!

21 posted on 03/24/2008 5:04:34 PM PDT by DCPatriot ("It aint what you don't know that kills you. It's what you know that aint so" Theodore Sturgeon))
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To: pallis

Wow! Glad you’re doing well! Good for you!


22 posted on 03/24/2008 5:06:06 PM PDT by DCPatriot ("It aint what you don't know that kills you. It's what you know that aint so" Theodore Sturgeon))
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To: DCPatriot

Hey there, DCP, you’re more than welcome.

One afterthought, if strokes run in your family, DO be careful if you are taking aspirin on a regular basis (to reduce the risk of heart attack or any other purpose) AND *if* you take any form of Ginkgo Biloba, my pharmacist advised me a long time ago that many people don’t realize that if aspirin (a natural blood thinner) and Ginkgo (an artery and vein dilator) combine, that it can -increase- the risk of stroke due to the tiniest veins in the brain becoming unable to prevent blood from ‘leeching out’ (not sure of a better way to describe it) into the brain tissues.

Now on the subject of diabetes, at some point you might want to look into some neat stuff called ‘Goji Juice’, it comes from a little berry in the Himalayans (and a lot of companies are marketing the daylights out of it ala Amway-style themes), one relative of mine was actually able to reduce the amount of insulin they were taking after drinking two ounces of Goji every day, as it definitely can drop your blood sugar. The purest Goji (IMHO) can be found at a website ‘www.freelife.com’, but be forewarned, the stuff isn’t cheap, lol!

Congrats on the weight loss, good luck FRiend!


23 posted on 03/24/2008 7:51:15 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: mkjessup
Thank you very much for your post.

I do take a Bayer every morning...going on a year now. And Metformin 500mg 2X day. No insulin. And Cozaar for the blood pressure. Jeez...AND Lipitor!

When you type that out, you realize how OLD you really are! LOL!

24 posted on 03/24/2008 7:58:18 PM PDT by DCPatriot ("It aint what you don't know that kills you. It's what you know that aint so" Theodore Sturgeon))
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To: mkjessup

OLE is one of my favorite herbal extracts. However, for hypertension reduction, I take celery seed extract, which is a natural diuretic. Lowers my diastolic BP by 10 points overnight; systolic even more. Celery seed extract has the benefit of not screwing up the potassium balance as do other diuretics.


25 posted on 03/24/2008 7:58:41 PM PDT by steve86 (Acerbic by nature, not nurture™)
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To: DCPatriot
When you type that out, you realize how OLD you really are! LOL!

Oh I know exactly what you mean, I'm not currently on any doctor-prescribed medicines, but one look at my medicine cabinet would convince anyone that I'm running a health food and supplment supply warehouse out of my home! LOL

If you remember a music artist by the name of Larry Groce and his tune "Junk Food Junkie", this YouTube video might amuse you! ;)

http://www.youtube.com/watch?v=rSUh2b1ufi4

Have a good rest o' the week!
26 posted on 03/24/2008 8:18:39 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: steve86

Re, Celery Seed Extract?

You are absolutely right about that, and I should have mentioned that too as an option in dropping blood pressure - I’ve tried it myself and the only effect I didn’t care for was that I found myself whizzing like the proverbial race horse!

But it’s good stuff, no question about it!


27 posted on 03/24/2008 8:20:02 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: neverdem

interesting


28 posted on 03/24/2008 8:21:42 PM PDT by kalee (The offenses we give, we write in the dust; Those we take, we write in marble. JHuett)
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To: mkjessup

Yes, it is definitely not one of those herbs that “does nothing”. I’ve worn out the carpet on the way to the bathroom.


29 posted on 03/24/2008 8:51:54 PM PDT by steve86 (Acerbic by nature, not nurture™)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Lord Winston accuses Catholic church of 'lying' over controversial Embryo Bill

Physicists show electrons can travel over 100 times faster in graphene than in silicon

TB Patients Chafe Under Lockdown in South Africa

FReepmail me if you want on or off my health and science ping list.

30 posted on 03/24/2008 10:26:07 PM PDT by neverdem
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To: mkjessup

My daughter owns a potpourri manufacturing company and has a barrel of olive leaves. I need to google to see how to make the extract—if possible.


31 posted on 03/25/2008 5:19:06 AM PDT by Conservativegreatgrandma
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To: mkjessup

I think my SIL takes red rice yeast.


32 posted on 03/25/2008 5:20:05 AM PDT by Conservativegreatgrandma
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To: BunnySlippers
Where does one get Olive Leaf Extract?

You have to catch a lot of doves at the peace marches.

33 posted on 03/25/2008 5:22:42 AM PDT by ovrtaxt (Member of the irate, tireless minority, keen on setting brushfires of freedom in the minds of men.)
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To: mkjessup
MI

Sounds like our house. We don't go to doctors and deal with any minor malady that may arise by googling or going to curezone.com.

I've found castor oil packs. Worked for a sore hip. I refuse to take drugs. They cure nothing.

34 posted on 03/25/2008 5:25:13 AM PDT by Conservativegreatgrandma
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To: mkjessup

Here is another BP solution you can try:

http://www.drwhitaker.com/MainSite/HealthCenter
.aspx?HealthCenter=JWHH_HC%20Blood%20Pressure%20Health


35 posted on 03/25/2008 6:45:40 AM PDT by antisocial (Texas SCV - Deo Vindice)
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To: pallis

I just read an article in our newspaper about this kind of surgery being very effective in treating diabetes. I can’t remember the details but I think it had something to do with the “communications” between the pancreas (where insulin is made) and the gut. Even if people re-gain weight they lost after the surgery, the improvement in blood sugar control remains. Sounds like you were on the ‘cutting edge’ with your surgery. [no pun intended ;)]


36 posted on 03/25/2008 6:55:53 AM PDT by iceskater
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To: mkjessup

Would you please add me to your ping list? Thanks!


37 posted on 03/25/2008 7:02:09 AM PDT by AxelPaulsenJr (God Bless George W. Bush)
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To: neverdem

bookmark


38 posted on 03/25/2008 7:35:08 AM PDT by traviskicks (http://www.neoperspectives.com/Ron_Paul_2008.htm)
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To: AdmSmith; Berosus; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; george76; ...

Thanks neverdem. The whole notion of a hypertension vaccine makes me nervous.


39 posted on 03/25/2008 9:01:45 AM PDT by SunkenCiv (https://secure.freerepublic.com/donate/______________________Profile updated Saturday, March 1, 2008)
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To: neverdem

Thanks for the ping...this might be something to look at...


40 posted on 03/25/2008 11:15:29 AM PDT by Ernest_at_the_Beach (No Burkas for my Grandaughters!)
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To: SunkenCiv

ANY vaccine makes me nervous much less one for blood pressure. This is more medical sophistry. My 17 yr old daughter has had no vaccines of any kind, and she’s a picture of health.


41 posted on 03/25/2008 11:47:27 AM PDT by Rennes Templar ( Never underestimate the difficulty of changing false beliefs by facts.)
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To: neverdem

They should test this vaccine against aggressive persons in prisons. If angiotensin II goes down there will be lower level of Vasopressin and thus lower aggressive behavior of males against other males.


42 posted on 03/25/2008 1:58:11 PM PDT by AdmSmith
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To: Rennes Templar
My 17 yr old daughter has had no vaccines of any kind, and she's a picture of health.

Yes, as long as she is not exposed to pathogens. This is extremely dangerous, you should talk to your physician.
43 posted on 03/25/2008 2:00:44 PM PDT by AdmSmith
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To: AdmSmith

You, like most Americans, are caught in the pathogen fear paradigm. She has traveled the world and been exposed to all kinds of things. Her immune system functions at a high level as she does not eat the standard American diet. Fact is, vaccines side effects are responsible for more disease than they proport to prevent.


44 posted on 03/25/2008 2:19:30 PM PDT by Rennes Templar ( Never underestimate the difficulty of changing false beliefs by facts.)
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To: Rennes Templar
Fact is, vaccines side effects are responsible for more disease than they proport to prevent.

As proven by all the kids I see stricken by polio....

45 posted on 03/25/2008 2:22:00 PM PDT by whd23
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To: 2Jedismom

Interesting...


46 posted on 03/25/2008 2:24:35 PM PDT by RosieCotton
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To: Conservativegreatgrandma
My daughter owns a potpourri manufacturing company and has a barrel of olive leaves. I need to google to see how to make the extract—if possible.

Good evening CGGma!

Sorry for the delay in getting back to you, if convenient - could you let me know how you make out with making your own olive leaf extract?

I've had pretty good luck with the store bought variety but if there is a natural alternative, that is always preferable.
47 posted on 03/25/2008 6:40:31 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: Conservativegreatgrandma
I think my SIL takes red rice yeast.

I've not heard of that, I'll look up the particulars, thanks!
48 posted on 03/25/2008 6:41:21 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: Conservativegreatgrandma
I refuse to take drugs. They cure nothing.

I try to avoid them if at all possible. Many moons ago, I had an acid reflux issue and my doctor gave me some samples of Tagamet, I tried it, and it did seem to cut down on stomach acid, all was well and suddenly I began having some very odd perceptions of distance, space, time, etc., I called up the doctor and he says "oh yeah, some people experience confusion and hallucinations, you might want to cut the tablet in two and see how that works, ok?"

I went him one better. I pulverized the tablets with a hammer and flushed the whole mess down the toilet. No more Tagamet for me! LOL

By the way, here is a useful website I've found helpful:

http://www.wrongdiagnosis.com

49 posted on 03/25/2008 6:48:28 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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To: antisocial

Thanks for the link FRiend! It’s appreciated! :)


50 posted on 03/25/2008 6:49:24 PM PDT by mkjessup (This year's presidential choices: "Speak No Evil, See No Evil, and Evil")
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