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Scientists discover new species of Ebola virus
biologynews.net ^ | November 20, 2008 | NA

Posted on 11/21/2008 9:35:44 PM PST by neverdem

Scientists report the discovery of a new species of Ebola virus, provisionally named Bundibugyo ebolavirus, November 21 in the open-access journal PLoS Pathogens. The virus, which was responsible for a hemorrhagic fever outbreak in western Uganda in 2007, has been characterized by a team of researchers from the Centers for Disease Control and Prevention in Atlanta, Georgia the Uganda Virus Research Institute; the Uganda Ministry of Health; and Columbia University.

Ebola virus infection in humans causes severe disease for which there is presently no vaccine or other treatment. Case fatalities range historically between 53 and 90%. Therefore, research efforts into the Ebola virus genus and potential diagnostics are ongoing, with the discovery of Bundibugyo ebolavirus representing one of the latest pieces added to this puzzle.

The new virus is genetically distinct from all other known Ebola virus species, differing by more than 30% at the genetic level. More traditional ELISA-based assays detected the new virus; however, the unique nature of this virus created initial challenges for traditional Ebola virus molecular diagnostic assays and genome sequencing approaches. To determine the genetic signature of this new Ebola virus species, scientists used a recently developed random-primed pyro-sequencing approach, quickly determining the genetic sequence of over 70% of the virus genome.

Knowledge of this sequence then allowed for the rapid development of a sensitive molecular detection assay which was deployed to the field as part of the outbreak response. This draft sequence also allowed for easy completion of the whole genome sequence using a traditional primer walking approach and prompt confirmation that this virus represented a new Ebola virus species. Current worldwide efforts to design effective diagnostics, antivirals and vaccines will need to take into account the distinct nature of this new member of the Ebola virus genus.

Source : Public Library of Science


TOPICS: Culture/Society; Government; News/Current Events; Technical
KEYWORDS: ebola; health; medicine; microbiology
Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
1 posted on 11/21/2008 9:35:45 PM PST by neverdem
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To: neverdem

Bundibugyo Obama. Another half-sister discovered? How many more does he have?


2 posted on 11/21/2008 9:38:12 PM PST by ProtectOurFreedom
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To: Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe
Study of ancient and modern plagues finds common features

micro ping

3 posted on 11/21/2008 9:40:24 PM PST by neverdem (Xin loi min oi)
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To: null and void

micro ping


4 posted on 11/21/2008 9:43:01 PM PST by neverdem (Xin loi min oi)
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To: neverdem

If God decides to use this as a plague, watch out.


5 posted on 11/21/2008 9:51:27 PM PST by pray4liberty (Always vote for life!)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping (new Ebola virus) Thanks, neverdem!


6 posted on 11/21/2008 10:15:19 PM PST by Smokin' Joe (How often God must weep at humans' folly.)
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To: neverdem

Not totally true that there is no treatment.

During one of the outbreaks, I think in Uganda, they extracted blood serum from a survivor, and used it on current cases.

IIRC, the few times they tried it, it worked. Something in the blood of the survivor ramped up the immune system of the newly infected folks. Kinda like an anti-venin, I guess.


7 posted on 11/21/2008 10:26:46 PM PST by djf (The harsh reality of life is that reality is harsh.)
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To: pray4liberty
"If God decides to use this as a plague, watch out."

You are certainly right about that. So far, the only reason why it doesn't spread to more people is because it's too deadly. It kills so fast, it doesn't go very far. The people that get infected die before they can spread it to others.

8 posted on 11/21/2008 10:38:05 PM PST by KoRn
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To: neverdem

I’m sorry, I’m at my limit for worrying about things right now. Please come back when things look like they might be getting better:)


9 posted on 11/22/2008 12:02:53 AM PST by The Antiyuppie ("When small men cast long shadows, then it is very late in the day.")
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To: The Antiyuppie
We were in western Uganda (BTW a beautiful country) with much of family for gorilla/chimp treking in January 2008. They were reporting the outbreak to be Marberg’s disease at the time which is less infectious though still quite deadly. Sobering to consider what might have been and thank god for good luck.
10 posted on 11/22/2008 12:39:23 AM PST by SERUM10
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To: ProtectOurFreedom
Bundibugyo Obama. Another half-sister discovered? How many more does he have?

They could name this disease after him.Hell,they're renaming everything else Obama these days.This would actually be more fitting.

11 posted on 11/22/2008 1:51:51 AM PST by Uncle Meat
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To: neverdem

Ho boy! Just when we getting used to the old ebola!


12 posted on 11/22/2008 2:58:53 AM PST by count-your-change (You don't have be brilliant, not being stupid is enough.)
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To: neverdem
What the hell! Guess that it's not too early. And it's only fair...

obama fault!

13 posted on 11/22/2008 3:41:14 AM PST by skimbell (Life, Liberty and the pursuit of all who threaten either.)
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To: neverdem

Maybe Ebola’s mutating into something less nasty?


14 posted on 11/22/2008 4:45:38 AM PST by mewzilla (In politics the middle way is none at all. John Adams)
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