Naltrexone (hydrochloride), an opioid antagonist, is a synthetic congener of oxymorphone with no opioid agonist properties. It's those agonists that people abuse.
Bupropion is an antidepressant medication.
Orexigen Diabetes Drug Helps Diabetes Patients Lose Weight, Cut Glucose
It’s Welbutrin. And its also used to treat smoking. I guess they are trying to solve overeating with an antidepressant. Either that or they are suggesting that diabetes and Atypical depression are linked.
Type I diabetes also has its genetic component ~ the Finns, for example, have the world's highest incidence of Type I and it is believed that there is a selective advantage for it in what turns out to be the Earth's most rigorous climate for the largest number of people. Some folks develop Type I, and some develop something short of that, but it's not Type II ~ just a shortage of insulin ~ readily handled with supplemental insulin input.
Going beyond that, the genetic incidence of Type II, is, in general, about 5%. With 300 million people the US can have 15 million diabetics. Half of them have been diagnosed already. The other half simply haven't developed it yet.
To have 44 million diabetics in the US we'd need a population of about 900 million people!