Found this elsewhere on the web
In March of 1980, the obstreperous militant leftist Oscar Romero, Archbishop of San Salvador, was assassinated outside of the city’s main cathedral. The assassin employed a scoped, turn-bolt rifle chambered for the .22 LR round, and fired from a distance of 80 meters. Romero was killed by a single bullet to the heart.
And -
F.B.I. statistics clearly show more people in the U.S. die, accidentally or intentionally, every year from .22 LR gunshot wounds than any other round.
I owuld note that this stat may be driven more by lack of pre-hospital care or that folks simplely own more 22LR weapons than not.
But - get shot by anything - and not have a truma center nearby - and you may become parts of these grim statistics..
Also - The bulk of sound-suppressed pistols designed for covert use by clandestine operatives have been chambered for 22LR - think Mossad.