[mware]

The Nobel Prize in Physiology or Medicine 2012
Sir John B. Gurdon, Shinya Yamanaka
The Nobel Prize in Physiology or Medicine 2012Summary
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Press Release
2012-10-08

The Nobel Assembly at Karolinska Institutet has today decided to award

The Nobel Prize in Physiology or Medicine 2012

jointly to

John B. Gurdon and Shinya Yamanaka

for the discovery that mature cells can be reprogrammed
to become pluripotent

Summary
The Nobel Prize recognizes two scientists who discovered that mature, specialised cells can be reprogrammed to become immature cells capable of developing into all tissues of the body. Their findings have revolutionised our understanding of how cells and organisms develop.

John B. Gurdon discovered in 1962 that the specialisation of cells is reversible. In a classic experiment, he replaced the immature cell nucleus in an egg cell of a frog with the nucleus from a mature intestinal cell. This modified egg cell developed into a normal tadpole. The DNA of the mature cell still had all the information needed to develop all cells in the frog.

Shinya Yamanaka discovered more than 40 years later, in 2006, how intact mature cells in mice could be reprogrammed to become immature stem cells. Surprisingly, by introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, i.e. immature cells that are able to develop into all types of cells in the body.

These groundbreaking discoveries have completely changed our view of the development and cellular specialisation. We now understand that the mature cell does not have to be confined forever to its specialised state. Textbooks have been rewritten and new research fields have been established. By reprogramming human cells, scientists have created new opportunities to study diseases and develop methods for diagnosis and therapy.

[GBA]

We now understand that the mature cell does not have to be confined forever to its specialised state.

Not as cool as whatever obama did to 'earn' his prize, but I am astounded by their research. God did some amazing work creating us humans.

Hats off to those who "discover" and show us the intricate details, while changing our lives for the better along the way!

[nomad]

But the newer mRNA reprogramming method is much safer and quicker, the ghouls won`t spread the word, there`s no potential viral contamination of the host cell`s genome with the mRNA method, you need to expand and do extensive genetic testing before you dare to use any viral re-programed stem cells.

[little jeremiah]

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I meant to ping out an article about the Nobel Prize given to the scientists who researched using adult cells can be used for medicine instead of cells from aborted babies. There is no need for this cannibalism of using aborted babies' cells, and from what I've read, it's useless anyway.