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Soy's Negative Impact on The Thyroid
About ^ | by Mary J. Shomon

Posted on 07/09/2003 6:43:46 PM PDT by webber

Soy's Thyroid Dangers

A Look at the Dangers of Soy to the Health of Your Thyroid

by Mary J. Shomon

Health and nutrition magazines tout the benefits of soy as a cure-all for women's health, hormonal problems, cancer prevention, weight loss, and many other problems. The reality, however, is that promotion of soy may be more a matter of business and marketing, rather than recommendations based on sound scientific evidence.

Isoflavones, the key components of soy that make them so potent as a possible substitute for hormone replacement, mean that soy products, while touted as foods and nutritional products -- often are used and act like a hormone.

If you have a diagnosed or undiagnosed thyroid problem, or a history of autoimmune disease, overconsumption of soy isoflavones can potentially trigger a thyroid condition. Soy foods can worsen an existing diagnosed thyroid problem in many people. In both cases the symptoms such as fatigue, weight gain, and depression or moodiness are often overlooked and hard to diagnose.

A recent study found that as millions of Americans -- perhaps as many as more than 10 million -- have an undiagnosed thyroid condition. The vast majority of thyroid patients are women over 40. This is the same group that, responding to marketing claims that promote soy as helping to prevent breast cancer, reducing the risk of high cholesterol or heart disease, or as a treatment for symptoms of menopause, are turning to soy foods and isoflavone supplements in vast numbers.

Here is more information regarding soy and its relationship to the thyroid.

FDA's Soy Experts Speak Out Against Soy

"There is abundant evidence that some of the isoflavones found in soy, including genistein and equol, a metabolite of daidzen, demonstrate toxicity in estrogen sensitive tissues and in the thyroid. This is true for a number of species, including humans.

Additionally, isoflavones are inhibitors of the thyroid peroxidase (TPO) which makes T3 and T4. Inhibition can be expected to generate thyroid abnormalities, including goiter and autoimmune thyroiditis. There exists a significant body of animal data that demonstrates goitrogenic and even carcinogenic effects of soy products. Moreover, there are significant reports of goitrogenic effects from soy consumption in human infants and adults."

Official Letter of Protest to the FDA

Letter of protest from researchers Daniel Doerge and Daniel Sheehan, two of the Food and Drug Administration's (FDA) key experts on soy, to the FDA, protesting the health claims approved by the FDA on soy products.

America's Foremost Alternative Doctor Warns:

RE: Soy
America's leading alternative doctor, Dr. Andrew Weil, has said about soy, at his Ask Dr. Weil website:

"…you're unlikely to get too many isoflavones as a result of adding soy foods to your diet -- but you probably will take in too much if you take soy supplements in pill form. At this point, I can only recommend that you avoid soy supplements entirely."

Study Shows That Too Much Tofu Induces "Brain Aging"

From the Honolulu Star-Bulletin

"A Hawaii study shows a significant statistical relationship between two or more servings of tofu a week and "accelerated brain aging" and even an association with Alzheimer's Disease, says Dr. Lon White." "...these are not nutrients. They are drugs. They will have some benefits and some negative things."

Don't Go Overboard With the Soy Foods!

David Zava, Ph.D., a biochemist and an experienced breast cancer researcher stated in an interview:

"In studying the literature on soy I found there are about five types of plant chemicals [antinutrients] in the soybean that can be toxic to humans if they are not removed by special processing… the fifth antinutrient in soybeans is called a goitrogen.

This is a chemical that latches on to iodine, preventing it from absorbing into the body from the gastrointestinal tract. Iodine is needed to make thyroid hormone. Low thyroid function has been associated with poor brain development.

Anyone who has been deficient in thyroid hormone understands quite well what impact this can have on normal brain function, especially at a time in life as we grow older and "fuzzy thinking" creeps into our vocabulary."

North American Menopause Society Won't Endorse Soy Products

In a press statement, the North American Menopause Society has said:

"Our review found that scientific data are inconclusive regarding whether the observed health effects in humans are attributable to isoflavones alone or to isoflavones plus other components in whole foods… women may wish to consume whole foods that contain isoflavones, especially for potential cardiovascular benefits. However, scientific data supporting the use of isoflavones for hot flashes are conflicting, and inadequate data exist to evaluate their effect on breast and other female cancers, bone mass and vaginal dryness… Our evaluation also pointed out that a level of caution needs to be observed, especially in the use of isoflavone supplements, powders and pills…More studies documenting benefits and safety need to be conducted.''

Research Shows Soy's Effects

American Journal of Clinical Nutrition, Vol 68, 1431S-1435S:

"Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast"

-- Study showed that short-term use of dietary soy stimulated breast cell proliferation, which can increase the risk of breast cancer.

Anti-thyroid isoflavones from soybean

November 1997 article from Biochem Pharmacol in which "it was observed that an … extract of soybeans contains compounds that inhibit thyroid peroxidase- (TPO) catalyzed reactions essential to thyroid hormone synthesis."

Breast and soy-formula feedings in early infancy and the prevalence of autoimmune thyroid disease in children

April 1998 article from the J Am Coll Nutr. that documents the association of soy formula feedings in infancy and autoimmune thyroid disease.

Leading Expert Warns of Soy-Thyroid Connection in Bestselling Book

In the bestselling book - "Living Well With Hypothyroidism: What Your Doctor Doesn't Tell You . . . That You Need to Know", leading soy expert Dr. Mike Fitzpatrick was profiled.

"Dr. Mike Fitzpatrick is an environmental scientist and phytoestrogen researcher who has extensively researched the issue of soy formulas, and the impact of soy consumption on thyroid function. Dr. Fitzpatrick introduced me to a little-known fact that can have substantial impact on people with hypothyroidism and the population in general -- overconsumption of soy products has the potential to impair thyroid function.

Dr. Fitzpatrick is so concerned that he is calling for soy formula manufacturers to remove the isoflavones -- the agents that are most active against the thyroid -- from their products.

There are also concerns for adult consumption of soy products. One UK study involving premenopausal women gave 60 grams of soy protein per day for one month. This was found to disrupt the menstrual cycle, with the effects of the isoflavones continuing for a full three months after stopping the soy in the diet.

Another study found that intake of soy over a long period causes enlargement of the thyroid and suppresses thyroid function. Isoflavones are also known to modify fertility and change sex hormone status, and to have serious health effects -- including infertility, thyroid disease or liver disease -- on a number of mammals… Dr. Fitzpatrick believes that people with hypothyroidism should seriously consider avoiding soy products, and predicts the current promotion of soy as a health food will result in an increase in thyroid disorders."

Soy Researcher is Even 'Very Concerned'

"There's a tendency in our culture to think if a little is good, then a lot's better," says Mary Anthony, a soy researcher at Wake Forest University School of Medicine in Winston-Salem, N.C. "But I personally am very concerned about isoflavone pills and soy protein supplemented with extra isoflavones."

Isoflavones, after all, seem to act like hormones or drugs in our body--even if for regulatory purposes they are classified as "Nutritional Supplements."




TOPICS: Culture/Society; Extended News; Miscellaneous; Technical; Unclassified
KEYWORDS: health; soy
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To: Finny
Oh -- and FWIW, I love tofu. When I was a kid, I used to eat it just plain out of the little box. Mmmm! Along with sheets of Japanese seaweed, right out of the package. Yum.
21 posted on 07/09/2003 7:43:54 PM PDT by Finny (God continue to Bless G.W. Bush with wisdom, popularity, and success. Amen.)
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To: Robert_Paulson2
Does this mean I can no longer enjoy sushi with soy sauce and wasabi? preposterous.

SOy sauce is a highly processed form of soy, of which you consume extremely small amounts. So I wouldn't worry. However Soy milk, soy chips, soy cereal and (especially) soy nuts contain far more isoflavones, and are thus apparently more damaging to your thyroid.

22 posted on 07/09/2003 7:48:43 PM PDT by montag813
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To: Finny
Good point about the fact that Japanese have been eating lots of soy for a long time

The Japanese have the highest rate of lympthatic cancer (the thyroid is a major part of this) in the world, as well as the second highest rate of stomach cancer in the world. Both of these facts may be in part attributable to the higher concentration of soy in the Japanese diet. The Chinese do not consume raw soy (like "edamame") or tofu in large quantaties. The Chinese also have a far smaller incidence of these cancers. Coincidence?

23 posted on 07/09/2003 7:52:30 PM PDT by montag813
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To: webber
No one has to persuade me to leave tofu alone, but I like a little Teriyaki sauce on my steak.
24 posted on 07/09/2003 7:53:41 PM PDT by Cicero (Marcus Tullius)
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To: Finny
You must live in a warm place to swim every morning.
25 posted on 07/09/2003 7:57:43 PM PDT by Aria
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To: Finny
she had eggs (plural) nearly every day and plenty of bacon, too. Most of her descendents have led equally healthy lives. But she was a real stickler for eating balanced meals, and moderate portions,

I remember the days of moderate portions, too. My mother used to think that scrambling 4 eggs and frying 8 slices of bacon was enough to feed 5 of us. We thought that was just fine.
Now if I go out to a diner, a single serving is 2-3 eggs, 3-4 slices of bacon, and a ton of extras like fried potatoes or pancakes and toast or muffins. No wonder we're all fat.

26 posted on 07/09/2003 7:57:51 PM PDT by speekinout
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To: webber
I will switch from soy protein.
27 posted on 07/09/2003 8:06:09 PM PDT by larryjohnson
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To: webber
There are several common foods, condiments, that can give a person a buzz. Hot peppers do this, so does nutmeg, and that can be a nasty one. Soy sauce or worchester [woozy it is called in jest] sauce is another. Take it easy on these, although the hot pepper is usually self limiting and not so much apt to be abused. Those who staff the ER don't want to see you there with a tragic nutmeg overdose.
28 posted on 07/09/2003 8:14:43 PM PDT by RightWhale (gazing at shadows)
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To: xm177e2
I don't think a little soy sauce is enough to hurt you, but eating big chunks of soy as a meat substitute is probably not great.

This brings to mind an old Tennessee recpie for cooking wild duck. Of course you pluck and clean the duck, then stuff it with herbs and tie the legs together. Next, you coat it with bar-b-que sauce and - I kid you not - you wrap the entire duck in COW PIES!!!

Next, you bake this entire concoction over a fire for about 90 minutes. After 90 minutes you carefully remove the duck from the fire, remove the hardened outer shell from the duck, throw the duck away, and eat the remaining baked cow pie ... because ANYTHING is better than a damned duck!

29 posted on 07/09/2003 8:34:46 PM PDT by The Duke
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To: webber
Marking...
30 posted on 07/09/2003 10:30:03 PM PDT by tubebender (FReepin Awesome...)
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To: montag813
The Chinese do not consume raw soy (like "edamame")............


Edamame is cooked soybeans from the field. Cooked in the pod
31 posted on 07/10/2003 3:24:16 AM PDT by dennisw (G-d is at war with Amalek for all generations)
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To: Servant of the Nine
Tofu kills!

No, it just tastes that way (Sweatsock flavor Jello)

LOL.... I don't like it either, though I've tried to cook it many different ways. For me, it's not the taste, it's the consistency that I just can't choke down. Even the extra-firm makes me gag.

I tried making jerky out of it once (marinated it, thinly sliced it, then baked it) but the wet "sputtering" of it grossed me out. It took HOURS but I finally got something I could eat out of it. I gave up after that.

LQ

32 posted on 07/10/2003 4:35:15 AM PDT by LizardQueen
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To: montag813
Sure doesn't seem like one. In any case, the majority of soy products are now off my menu. I already have to deal with lymphedema and am fighting anything that aggravates this condition. Maybe soy does also.
33 posted on 07/10/2003 4:23:46 PM PDT by Ladysmith (Land of the Free Because of the BRAVE!)
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To: Servant of the Nine
"Did any of these people notice that everyone in the orient has soy in one form or another in every meal for their entire lives?"

That's a bunch of "CRAP". Soy products are used sparingly in the Orient. It's the Americans who have been successfully brainwashed into believing that soybean products are used significantly in the oriental diet. The use of Soy Products have been reduced in favor of "Western Cuisine" and they are living longer with less disease....."amazing"!

34 posted on 07/11/2003 6:25:12 PM PDT by webber
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To: Servant of the Nine
"Only since Commodore Perry. Until that time Japan below the level of the nobility was essentially Bhuddist and vegetarian."

Where do you people get this garbage from? Washington Post? New York Times? Clinton News Network?

35 posted on 07/11/2003 6:29:35 PM PDT by webber
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To: Robert_Paulson2
I enjoy soy...on a 1 degree of separation concept...feed the soy to some 4 legged creature, or a 2 legged one that has feathers...and I'll eat those after slaughter.
36 posted on 07/11/2003 6:32:25 PM PDT by Keith in Iowa (Tag line produced using 100% post-consumer recycled ethernet packets,)
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To: webber
Be carful, your rectum is on fire.

So9

37 posted on 07/11/2003 8:08:49 PM PDT by Servant of the Nine (Real Texicans; we're grizzled, we're grumpy and we're armed)
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