Certainly. There were specific reasons why God suggested to avoid certain blend proportions of wool and linen. It could have had to do the integrity of the mix (wool is animal and linen is plant) or it could have had to do with the climate at the time. But generally if God says not to do it's undoubtedly correct.
I have a strong suspicion that the reason was much more practical than that: perhaps people were mixing expensive linen threads with cheap wool ones, and then selling "linen" garments to unsuspecting customers at vastly inflated prices.
Sort of like the Chinese spiking foods with melamine ....