Further studies? Yes. But there were 108 in this study, half randomized to the treatment group and half to the control group. So two of the 54 in the treatment group had this amazing response. But 52 didn't.
Same old, same old as every clinical trial I've ever worked in or heard about... It should always make us suspicious when a couple of overenthusiastic researchers start counting their Nobel Prizes before they hatch.
Is there data on the other 52? I didn’t notice it in the article. These two patients certainly had a dramatic response. I suppose it’s possible they had an unsually good response to the hormone treatment. But the article indicates they were not expected to live long without the study treatment.
Same old, same old as every clinical trial I've ever worked in or heard about... It should always make us suspicious when a couple of overenthusiastic researchers start counting their Nobel Prizes before they hatch.
Do an author search of Blute m, kwon e at PubMed.
They have 36 other citations. These are two good case reports, and good PR for Mayo.
They have found a great deal of genetic variation within just particular types of cancer such as prostate. This monoclonal antibody might be good for only one subtype. Who knows? But I'll bet money that they write it up. It depends on the protocols they agreed to follow when they started the study, e.g. how long to follow the patients, what they would agree as endpoints, etc. Then they have to find a journal that wants to print it.