All the Republican candidate has to do is remind the voters of Obama's bribe to Landrieu when Obamacare came up for a vote.
If the GOP already has the 6 or more senate gains on Election Day, then miss Mary will lose the runoff by a landslide 3 weeks later. Conversely, if control of the senate hangs in the balance, the rats and msm will move heaven and earth to steal this election.