That would depend on her opponent. If Paul can't get the state GOP to turn the selection from a primary to a caucus then he's got to make a choice. If he chooses president then who do the GOP have to run in his place?
Rand Paul needs to run for the Senate seat again. He is NOT going to be the GOP nominee. If he has to give up his reelection bid for the Senate to pursue the GOP nomination for Prez, he’d be stupid to do so.
There are plenty of folks who could beat Alison Lundergan Grimes. We've got a lot more of a bench than we used to have here, and we should have a good election this year (our statewide offices are all up). I hope there is a real effort to remove her from her current office, which I think is also very doable.