But not in humans. Your body produces all the enzymes it needs. Now, let's clarify EPSPS in animals. First, The toxicities of glyphosate have been thoroughly studied in mammals over the short and long term. Bioaccumulation and elimination have also been studied. Glyphosate has a very low level of toxicity in mammals and is not retained to a significant degree in animal tissue. Glyphosate is practically non-toxic by ingestion. The LD50 is greater than 500mg per kg in rats. That's really high. Glyphosate is probably the safest and most effective herbicide available.
Animals do not contain the molecular target (EPSPS) of glyphosate. Yes, the intestinal flora of some animals do contain EPSP but that has also been studied extensively. The results show that glyphosate ingestion has no significant effect on rumen fermentation.
All the hand wringing about this product is just that. Glyphosate is so far and away safer than what we've used in the past that you'd think the chemical illiterates would be thankful for its development. But no, as they have done for centuries, they continue to gnash and wail over things they don't understand.
“Yes, the intestinal flora of some animals do contain EPSP but that has also been studied extensively. The results show that glyphosate ingestion has no significant effect on rumen fermentation.”
Impossible to determine this for sure. There are hundreds of thousands of different gut flora and infinite possible interactions that change every microsecond.
Humans have consumed plants and microbes that use ESPS since we have existed. We are now spraying entire fields of our food with this poison that kills all of it.
Just because we think it only poisons “other” biology, does not mean it has zero impact on us. All is connected in ways we do not even begin to understand.
“But no, as they have done for centuries, they continue to gnash and wail over things they don’t understand.”
Because it is impossible to fully understand the impact of spraying and covering entire ecosystems with manmade chemicals that never existed in the biosphefore. It is folly to think we are smart enough to do such a thing and no amount of studies will make it a certainty. Man is too flawed to wield such power on all biology. Especially when trillions of dollars in personal gain are involved