[boris]

"FORGET ABOUT 1-SHOT STOPPING POWER. There is no such thing as it takes a brain or spine shot to effect a complete shutdown of a perp, both iffy under stress. Proper bullet placement and 'hit them til they go down' no matter the caliber should be how you train."

Oh, I am not so sure of that:

From my limited shooting of this little number, it has "near-one-shot" stopping power on the fellow who launches the rounds.

I don't think the guy at the other end would be in any shape to 'continue' if hit anywhere near a vital organ...

--Boris

[Pistolshot]

Take into account if the perp is high on meth, PCP, or even just on adreneline. NO cartridge will be a reliable 1-shot stopper.
Yes, that is an impressive weapon and cartridge, but not really concealable or practical.