Enbrel, Remicade and Humira. They're classified as "anti-TNF" drugs. My rheumatologist told me that 2 of 3 patients with RA respond to the drugs. They're also very expensive. $12-18k/year, but well worth it. You may have seen the commercials for Enbrel on TV.
Enbrel requires self-injection 2x/wk. Humira is self-injected once biweekly. Remicade is administered by IV in a hospital or doctor's office every 4-8 weeks. I'm using Remicade and having great results.
Anti-TNF is a name given to a new class of drugs available for the treatment of severe rheumatoid arthritis. Currently this group consists of three drugs, infliximab (trade name Remicade), etanercept (trade name Enbrel) and adalimumab (trade name Humira). These drugs work by blocking the action of TNF (tumour necrosis factor) a molecule responsible for increasing levels of inflammation in people with rheumatoid arthritis.
Not for use on other forms or arthritis, though.