Keyword: bloodpressure
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Blood pressure is closely monitored in hospitalized patients. Severely high blood pressure can lead to a heart attack, stroke, or damage blood vessels and organs including the heart, brain, kidneys and eyes. However, most hospitalized patients experience transiently elevated blood pressure without signs of organ damage, also referred to as asymptomatic hypertension, which is sometimes treated with blood pressure medications. In a retrospective cohort study, physician-researchers found that receiving intensive antihypertensive treatment as an inpatient was linked with greater risk of adverse events, particularly for patients receiving the medication intravenously as opposed to orally. "In the hospital, blood pressure is...
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Data from the phase III INTERACT3 study demonstrate that a new combination of treatments for stroke due to intracerebral hemorrhage (ICH) significantly improves the chances of surviving without major disability. The INTERACT3 study is the first-ever randomized controlled trial to show a clearly positive outcome for the treatment of ICH. Timely administration of the new treatment protocol—known as a Care Bundle—centered on the rapid control of high blood pressure, led to improved recovery, lower rates of death, and better overall quality of life. Professor Craig Anderson said, "Despite the high rates of ICH and its severity, there are few proven...
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Adults with hypertension, prediabetes, or type 2 diabetes, and who are overweight or obese, are at an increased risk of serious health complications. However, experts disagree about which dietary patterns should be recommended. Researchers randomized 94 adults with the aforementioned conditions, using a 2 x 2 diet-by-support factorial design, comparing a very low-carbohydrate (VLC) or ketogenic diet versus a Dietary Approaches to Stop Hypertension (DASH) diet. Additionally, they compared results with and without extra support activities, such as mindful eating, positive emotion regulation, and cooking education. Using intent-to-treat analyses, the VLC diet led to greater improvement in estimated mean systolic...
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In a recent Phytotherapy Research study, scientists review existing literature on edible mushrooms and their bioactive constituents and their impact on hypertension. Study: Edible mushrooms as potential functional foods in amelioration of hypertension. Image Credit: New Africa / Shutterstock.com Study: Edible mushrooms as potential functional foods in amelioration of hypertension. Image Credit: New Africa / Shutterstock.com The health benefits of mushrooms Edible mushrooms are enriched with nutritional bioactive compounds, dietary fiber, amino acids, sterols, proteins, vitamins, and minerals that can influence cardiovascular functions. These types of mushrooms are considered a common functional food that is present in different types of...
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Intensive blood pressure treatment significantly reduces the risk of adverse cerebrovascular events such as stroke. New research shows evidence of how the brain benefits from consistently lower blood pressure. The study is a follow-up analysis of the Systolic Blood Pressure Intervention Trial (SPRINT), a multicenter clinical trial that compared intensive systolic blood pressure control (target less than 120 mm Hg) versus standard control (target less than 140 mm Hg). SPRINT enrolled participants aged 50 or older with hypertension and without diabetes or a history of stroke. "Our study demonstrates that lowering systolic blood pressure to below 120 mm Hg is...
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New research has found that eating a handful of wild blueberries daily has health benefits, including lowered blood pressure, faster reaction time, and improved memory and brain cognition. The study involved a randomized, double blind, placebo-controlled trial of 61 healthy men and women aged 65 to 80, who drank a beverage made with 26 grams of freeze-dried wild blueberry powder (equivalent to about 178 grams of whole berries). Over twelve weeks, researchers found that volunteers who consumed the berry powder in drinks experienced better memory and an improved accuracy on attention tasks, as well as lower blood pressure. Also during...
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A new study of elderly patients showed that those who exercised in the evening experienced a greater decrease in blood pressure compared to those who exercised in the morning. The work also revealed the neurovascular mechanisms responsible for these findings. "Elderly patients or those with resistant hypertension or obesity don't always experience as much blood pressure benefit from exercise as other groups," said Leandro Brito, Ph.D. "For these patients, finding a more beneficial time to exercise may reduce their need for medication or help it work better." The study, which was conducted when Brito was a postdoctoral trainee at the...
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Pulmonary hypertension, or high blood pressure in the lungs, is a common complication of interstitial lung disease, an array of conditions that cause scarring of the lungs. Without treatment, it can be life-threatening. But currently, the only way to diagnose pulmonary hypertension definitively is through an invasive outpatient procedure called right heart catheterization, which measures pressures inside the heart and lungs using a small device inserted through a neck vein. The study identified which variables were the strongest predictors of pulmonary hypertension. It also found a combination of variables could predict the condition with high accuracy. In its latest study,...
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Strength training practiced with moderate to vigorous intensity two or three times a week is an effective way to mitigate arterial hypertension (high blood pressure), according to a study. The group analyzed over 21,000 scientific articles and conducted a Cochrane meta-analysis, considered the gold standard for systematic reviews. Cardiovascular diseases are the leading cause of death worldwide, and high blood pressure accounts for 13.8% of deaths from such diseases. Arterial hypertension is diagnosed when systolic blood pressure exceeds 140 millimeters of mercury (mmHg) and/or diastolic pressure exceeds 90 mmHg. "We were interested above all in the volume and intensity found...
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New research shows the chances of higher blood pressure increases exponentially, particularly for overweight middle-aged men, with every hour of sleep they lose or change to their regular nighttime routine. A new study is one of the first large-scale extended studies into the effect of variable sleep patterns on blood pressure. The study involved a global sample covering the equivalent of more than 2 million nights of home sleep data measured from 12,287 adults—88% of them men and, on average, overweight (BMI; 28±6kg/m2)—in their own homes using portable under-mattress sensor monitoring technology and remote blood pressure assessment. On average, each...
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A new study finds biological sex and time of day makes a difference in the effectiveness of diuretics—medications commonly prescribed to manage high blood pressure. The body's circadian clock and biological sex are two key factors in blood pressure management. The kidneys play a significant role in blood pressure regulation by managing fluid and electrolyte levels in the body. The body's circadian clock also regulates kidney function. Researchers explored how time of day and biological sex affect how well diuretic medications work. These drugs act on different renal transporter proteins to increase the amount of urine the body excretes. The...
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Patients with pulmonary arterial hypertension (high blood pressure in the arteries that supply the lungs, also called PAH) had approximately double the reduction in pulmonary vascular resistance (PVR) if they took the PAH medications macitentan (10 mg) and tadalafil (40 mg) together in a single tablet rather than either drug alone, according to research. Macitentan and tadalafil are among several drugs approved by the U.S. Food and Drug Administration for the treatment of PAH. Guidelines and previous studies suggest that using two or more agents to treat PAH can bring extra benefits. In the portion of the study that compared...
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High blood pressure disorders during pregnancy are associated with an increased risk of thinking problems later in life, according to a study. Researchers found that those with these disorders had a higher risk of cognitive problems in later life than those who did not have high blood pressure during pregnancy. They also found that those with preeclampsia, which is high blood pressure that develops halfway through pregnancy and usually involves the kidneys and other organs, may have an even greater risk of cognitive decline later in life, compared to those with gestational high blood pressure, a condition with high blood...
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Drinking coffee helps maintain low blood pressure. People who drink two or three cups of coffee a day have lower blood pressure than those who drink just one cup or none at all. This applies both to peripheral and central aortic pressure, i.e. the one closest to the heart. The investigation analyzed the association between coffee consumption and peripheral and central blood pressure parameters in a sample of the Italian population. "The results obtained show that those who regularly drink coffee have significantly lower blood pressure, both on peripheral and central levels, than those who do not drink it," explains...
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Among people who received more intensive treatment for high blood pressure, evaluations of MRI scans indicated a positive change in brain structures involved in its ability to clear toxins and other byproducts. The study is the first to examine whether intensive blood pressure treatment may slow, or reverse structural changes related to the volume of the brain's perivascular spaces, areas of the brain around the blood vessels that are involved in the clearance of toxins and other byproducts. "If the brain cannot properly clear toxins and metabolic byproducts, they will accumulate and may contribute to the development of dementia," said...
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Experienced a kidney stone 25 years ago. Doctor at that time went in invasively to get it and remove Three nights ago, I was struck with another kidney stone attack. Lasted about 2 hours in the middle of the night. 24 hours later. Another one. Could feel the pain and the stone moving farther south. Another one early this morning, still painful but I believe stone is making progress. Refuse to go to any clinic or hospital, what do my wise freeper friends suggest to speed up the process and alleviate the pain.
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A large stroke trial has shown that intensive blood pressure lowering after clot removal worsens recovery, stopped early due to the significance of the findings. Professor Craig Anderson said the rapid emergence of this effect suggested the more aggressive approach was compromising the return of blood flow to the affected area. "Our study provides a strong indication that this increasingly common treatment strategy should now be avoided in clinical practice," he said. Around 85 percent of strokes are ischemic strokes, caused by the loss of blood flow to an area of the brain due to a blockage in a blood...
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Cocoa only reduces blood pressure and arterial stiffness when they are elevated, a study finds. Cocoa flavanols have previously been found to lower blood pressure and arterial stiffness as much as some blood pressure medication. However, how effective flavanols are in everyday life in reducing blood pressure has remained unknown, as previous studies in this area have been performed in tightly controlled experimental settings. Surrey's new research reduces concerns that cocoa as a treatment for raised blood pressure could pose health risks by decreasing blood pressure when it is not raised, paving the way for it to be potentially used...
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An observational study led by Professor Hiroaki Kanouchi presents the first evidence that eating sunomono—a Japanese vinegared side dish—correlates to lower blood pressure categorization in men. "The benefits of vinegar in a healthy diet are well known. Our research is the first observational study of these benefits; we didn't ask participants to change anything," explained Professor Kanouchi. Previous studies have shown that subjects drinking 30 mL of vinegar daily had lower blood pressure but also lost weight that could account for the lower blood pressure. Sunomono is a traditional side dish made with sliced cucumber or seaweed in rice vinegar,...
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Structured aerobic exercise training over 12 weeks improves blood vessel function in people with stage 3 and 4 chronic kidney disease (CKD), according to a new study by physiologists at Emory University School of Medicine in Atlanta. Researchers also found that exercise reduced blood pressure reactivity in this population. The article is published ahead of print in the Journal of Applied Physiology. This study was conducted in 38 men—primarily Black men—and 10 women with CKD who were randomly split among a structured and a supervised group. The aerobic "spin" group rode stationary bikes and the non-aerobic group participated in stretching...
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