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Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a study. The current analysis pools data from 16 studies conducted between January 2000 and May 2023, evaluating hypertension incidence in 1,044,035 people from six countries who did not have a prior history of high blood pressure over a median follow-up of five years (follow-up ranged from 2.4 to 18 years). Short sleep duration was significantly associated with a higher risk of developing hypertension after adjusting for demographic and cardiovascular risk factors. Furthermore, the association was found to be even...

Women ages 45 years and older taking estrogen hormone therapy in pill form were more likely to develop high blood pressure than those using transdermal (topical, applied to the skin) or vaginal formulations, according to research. "We know estrogens ingested orally are metabolized through the liver and this can lead to higher blood pressure," said Cindy Kalenga, an M.D./Ph.D.-candidate This study involved a large group of over 112,000 women, ages 45 years and older. First, researchers investigated the relationship between route of estrogen-only hormone therapy administration and risk of developing high blood pressure at least one year after starting the...

Dementia is defined as the loss of cognitive functioning—including thinking, remembering, and reasoning. Currently, the treatment satisfaction for dementia is among the lowest and no drug therapy is available to cure the disease. Cognitive impairment has been linked to the consumption of excess table salt. The involvement of angiotensin II (Ang II)—a hormone that plays a key role in regulating blood pressure and fluid balance—and its receptor "AT1," as well as that of the physiologically important lipid molecule prostaglandin E2 PGE2 and its receptor "EP1" in hypertension and neurotoxicity is well-recognized). To this end, a recent study evaluated the aspects...

Just asking some insight on BP. For years I have had high blood. Never did anything with it even when told I was in danger. Last month my legs begin to feel weak and painful and tingling. I would wake up without a thing, then about 2 hours at work it would begin. No chest pains or shortness of breath. It would start to disappear when I went home. The next day I would again wake up with nothing but then it would start in my arms and hands. Legs would be slightly weak but no pain. My job is...

Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure. The study is published online today in Nature Communications. TNF has long been tied to inflammation, giving rise to the use of anti-TNF medications for chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and IBS. Now, after years of studying TNF's cell signaling functions in the vascular system, researchers found that TNF directly impacts how the smallest arteries constrict - and thus...

AND NOW . . . amidst billowing clouds of fragrant, aromatic first- and second-hand premium cigar smoke. . . it is time for . . . that harmless, lovable little fuzz ball, the highly-trained broadcast specialist, having more fun than a human being should be allowed to have, from behind the golden EIB microphone, firmly ensconced in the prestigious Attila-the-Hun chair at the Limbaugh Institute of Advanced Conservative Studies, serving humanity simply by showing up, and he’s not retiring until every American agrees with him, do NOT doubt him, with shrieks of joy at the mere mention of his name...

In this trailer released by WB, Dumbledore narrates the story of Tom Riddle. We see glimpses of the inferi, more orphanage footage, the gates of Hogwarts as Harry and Luna travel up to them, Harry under his invisibility cloak on the train, Dumbledore grabbing a chain from the cave, a close shot of Narcissa, Draco working on the wardrobe, explosions in Diagon Alley and fire at the Burrow, Harry battling off the Inferi, Fenrir Greyback, Harry shouting at Snape, the bridge collapsing, and another "Once again, I must ask too much of you, Harry."