Well space is not a pure vacuum ..it is full of gas and debris
And the solar system gravity would be pulling all that gas and debris INWARDS to the solar system
In effect creating a very slight gas and debris head wind the outgoing spacecraft would be flying in to
So you cannot calculate the drag of solar system gravity alone on anything outbound... you would have to account for gas and debris being drawn in to the solar system causing a gas and debris head wind
And the amount of gas and debris in that head wind is an unknown variable
I wonder when Pioneer 10 reaches heliopause, or if the astrophysicists can even say.