Well, For example. The 44 Mag only holds 6 rounds. The 45-70 lever might hold 4 or 5. Even the renowned Rem 700 308 deer gun. I have 6 or 8 deer in my yard much of the time.
I would say that if as in the old days with Buffalo Bill he was riding on a train and wanted to kill about 100 Buffalo he would use a “modern sporting rifle” aka 5.56 and have about 10-12 magazines full of M-855 green tip.
Lots of buffalos in Atlanta. I have the means to feed my family, though.