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A diet of essential amino acids could keep dementia at bay (General lack of essential amino acids is key)
Medical XPress / The National Institutes for Quantum Science and Technology / Science Advances ^ | Oct. 25, 2021 | Hideaki Sato et al

Posted on 10/25/2021 8:45:39 PM PDT by ConservativeMind

Japanese researchers showed that a low protein diet can accelerate brain degeneration in mouse models of Alzheimer's disease. More importantly, they found that Amino LP7—a supplement containing seven specific amino acids—can slow down brain degeneration and dementia development in these animals.

Dr. Makoto Higuchi explains, "In older individuals, low protein diets are linked to poor maintenance of brain function. Amino acids are the building blocks of proteins."

First, the researchers studied how a low protein diet affects the brain in mouse models of Alzheimer's disease, which generally demonstrate neurodegeneration and abnormal protein aggregates called "Tau" aggregates in the brain. They found that mice consuming a low protein diet not only showed accelerated brain degeneration but also had signs of poor neuronal connectivity. Interestingly, these effects were reversed after supplementation with Amino LP7, indicating that the combination of seven specific amino acids could inhibit brain damage.

Next, the research team examined how Amino LP7 affects different signs of brain degeneration in the Alzheimer's model. Untreated mice showed high levels of progressive brain degeneration, but Amino LP7 treatment suppressed neuronal death and thereby reduced brain degeneration, even though the Tau aggregates remained. According to Dr. Akihiko Kitamura, who also led this study, "Tau plaques in the brain are characteristic of Alzheimer's and most treatments target them. However, we have shown that it is possible to overcome this Tau deposition and prevent brain atrophy."

They observed that Amino LP7 reduces brain inflammation and also prevents kynurenine, an inflammation inducer, from entering the brain, thereby preventing inflammatory immune cells from attacking neurons. They also found that Amino LP7 reduces neuronal death and improves neuronal connectivity, improving brain function.

“Our study is the first to report that specific amino acids can hinder the development of dementia,” say Dr. Hideaki Sato and Dr. Yuhei Takado.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: aminoacids; dementia; eggs; fish; meat; protein
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Complete protein sources like meat, eggs, and milk proteins should be fine and have all essential amino acids. Amino acid supplements have already converted or made the whole proteins into the amino acids our bodies actually need.

I couldn’t find the official list of only seven essential amino acids in this supplement, but one person on a site said it was likely Leucine, Isoleucine, Phenylalanine, Lysine, Histadine, Valine, and Tryptophan.

Regardless, anything with all the essential amino acids should be more than is needed.

1 posted on 10/25/2021 8:45:39 PM PDT by ConservativeMind
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To: ConservativeMind

The FASEB/LSRO report on the safety of amino acids as dietary supplements concluded the following:

There is no nutritional rationale to the use of amino acids as dietary supplements, and such a practice can be dangerous.

https://www.ncbi.nlm.nih.gov/books/NBK209070/


2 posted on 10/25/2021 8:51:46 PM PDT by TexasGator (UF)
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To: ConservativeMind

Plus fish.

Low-protein diets are probably high in sugar, which really burns your brain out.


3 posted on 10/25/2021 8:53:29 PM PDT by Veto! (Political Correctness Offends Me)
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To: ConservativeMind

Those are the amino acids in lp7.

They’re all in an egg, true


4 posted on 10/25/2021 8:54:54 PM PDT by Mount Athos
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To: ConservativeMind

If your stomach agrees, it’s simple to use meat, fish or poultry to maintain a high protein diet.
If you cannot break that kind of whole food down, or if you chose to be a Vegetarian, then you must learn all about the wonderful world of protein powders or protein bearing foods, such as beans, kelp and dairy products.
If you are a strict Vegan, you must learn about the amino acids and how to properly consume them. That’s the most complicated way to nutrition.


5 posted on 10/25/2021 8:55:19 PM PDT by lee martell
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To: ConservativeMind

Really it is quite simple, My great grandfather hung out with Jonnny Appleseed aka John Chapman.

there was lots of great medicinal cider made with them apples.

and a lot less manufactured faux-food all around

Since I find myself wondering about various prion things from time to time, I guess that means I am not all the way gone yet.

Besides, you can imagine you are president so it can’t be all bad.


6 posted on 10/25/2021 8:58:23 PM PDT by algore ( )
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To: ConservativeMind

Why, that sounds like the *perfect amino* tab :-)


7 posted on 10/25/2021 8:59:25 PM PDT by Jane Long (What we were told was a “conspiracy theory” in 2020 is now fact. 🙏🏻 Ps 33:12 )
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To: ConservativeMind

Tryptophan....

Eat more Turkey?


8 posted on 10/25/2021 9:03:55 PM PDT by Paladin2 (Critical Marx Theory is The SOLUTION....)
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To: ConservativeMind

just a precaution for those with kidney issues, i believe high protein diets can be pretty rough on kidneys-


9 posted on 10/25/2021 9:19:50 PM PDT by Bob434
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To: ConservativeMind

*AHEM*.

SOMEBODY forgot all about tuna fish!

10 posted on 10/25/2021 9:23:04 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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To: ConservativeMind

I couldn’t find the official list of only seven essential amino acids in this supplement, but one person on a site said it was likely Leucine, Isoleucine, Phenylalanine, Lysine, Histadine, Valine, and Tryptophan.


I can’t even pronounce those things.
I’ll stick with meat, eggs and any other food that contains what I need.


11 posted on 10/25/2021 9:32:12 PM PDT by Maris Crane
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To: Bob434

A pound of 80/20 hamburger yields about 77g protein, and 1150 total calories.

I’m 74 and weigh about 180. The keto/carnivore gurus say I need about 150g protein per day (0.8g/lb), available from two pounds of ground beef.

I would need to eat three times that for it to become a problem.


12 posted on 10/25/2021 9:32:50 PM PDT by JohnnyP (Thinking is hard work (I stole that from Rush).)
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To: JohnnyP

a lot of folks get into high protein shakes, and amino acids, etc- and also eat a lot of meat- which is fine for folks with healthy kidneys- but those with kidney damage or disease need to be aware that such diets can create further damage-

Your intake with kidney failure or disease depends o n what stage- stage 4 failure, the stage right before end stage failure- proteins can really do some damage- they state that in stages 1-2-3, your dietary protein should be about 12-15% of calories- Stage 4 you should drop it to just 10%


13 posted on 10/25/2021 9:46:47 PM PDT by Bob434
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To: ConservativeMind

Eat more beef!


14 posted on 10/25/2021 10:06:03 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: ConservativeMind

bookmark


15 posted on 10/25/2021 10:20:17 PM PDT by GOP Poet (Super cool you can change your tag line EVERYTIME you post!! :D. (Small things make me happy))
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To: ConservativeMind

bookmark


16 posted on 10/25/2021 10:29:35 PM PDT by Cap Huff (1776 - Washington fought for us. Since 2016 Washington has fought against us . . . )
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To: ConservativeMind

I found this: “Quinoa is one of the most nutritious grains available today. In addition to being a good source of fiber, it contains all nine essential amino acids that your body needs from food. It also has a higher amount of lysine than wheat or rice, making it a better source of these amino acids than other grains.”


17 posted on 10/25/2021 10:47:54 PM PDT by jonrick46 (Leftnicks chase illusions of motherships at the end of the pier.)
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To: jonrick46

A serving of quinoa contains the following amino acids: isoleucine, leucine, lysine, phenylalanine, tyrosine, cysteine, methionine, threonine, histidine, tryptophan and valine.


18 posted on 10/25/2021 10:50:19 PM PDT by jonrick46 (Leftnicks chase illusions of motherships at the end of the pier.)
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To: jonrick46

Thanks for that tip and it looks like it’s also low enough in carbs to work with a “dirty” keto diet. Not for a daily intake but better than rice or tators.


19 posted on 10/25/2021 11:34:04 PM PDT by Boomer (Leftism is a mental illness wrapped in a perverse ideology resulting in insanity. FJB)
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To: jonrick46

Then why does it taste like crap?

CC


20 posted on 10/26/2021 5:46:41 AM PDT by Celtic Conservative (My cats are more amusing than 200 channels worth of TV.)
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