The word is shockingly racist for our times, we know it means white women.
The left is always so far ahead of us, the word Karen of course means white woman, and remember how it started mainly as a white woman who calls the mgr. over to straighten something out, and it includes calling the cops on something suspicious or any of the other very useful things that white women do that help bring order to our society.
Is it sometimes annoying or even wrong, of course, but as men and women we have to agree that women are a civilizing force and that prissy intolerance for disorder and imperfections in public spaces is part of the female value to civilization.
I always interpreted it as calling police or management over inconsequential matters, because...Karen.
Or about my legally concealed firearm if my jacket comes unbuttoned and she sees it.