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Study highlights long-term, low-grade intestinal inflammation after radiotherapy (Dietary fiber may prevent it)
Medical Xpress / University of Gothenburg / eBioMedicine ^ | Sept. 28, 2023 | Sravani Devarakonda et al

Posted on 10/01/2023 10:39:29 AM PDT by ConservativeMind

Patients who have undergone pelvic radiotherapy may live with low-grade chronic inflammation of the lower intestine 20 years after the treatment. This has been shown in a study.

Radiotherapy is often necessary to cure or slow down a cancer. Even though today's radiotherapies feature a high level of precision, healthy tissue in and around the radiation field is still affected.

The mucous membrane of the large intestine is normally protected against contact with bacteria in feces by a thin barrier of mucus. In the current study, researchers have shown that radiotherapy to the pelvic area affects this thin layer of mucus, allowing bacteria to come into contact with cells on the surface of the intestine. This could be a reason for the low-grade inflammation that the researchers also found in intestines that had been exposed to radiotherapy several years previously.

"It can be hard to detect low-grade inflammation," says Sravani Devarakonda. "We saw signs of low-grade inflammation as late as twenty years after radiotherapy."

It is common for those who have received radiotherapy for cancer of the cervix, prostate, or rectum, for example, to experience intestinal symptoms many years after completing their treatment. The severity ranges from tenesmus (a feeling of not having emptied the bowels properly despite multiple toilet visits), to very frequent diarrhea (15 times a day or more).

The study is based on samples from 28 people, including 24 cancer survivors.

Research is already being carried out to find ways of strengthening the intestines' resistance to radiotherapy, so that long-term symptoms which affect quality of life can be alleviated or even prevented entirely. In an extensive study involving more than 300 patients, researchers are trying to strengthen the protective mucosal barrier by adding extra dietary fiber to the diet before beginning radiotherapy.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: bowels; cancer; inflammation; radiotherapy
Low grade inflammation can exist in various places, including fat. In this case, it appears responsible for continued problems with all things colon related.

Dietary fiber, specifically soluble fiber, can help create this mucous barrier in the gut. This can happen with people who never had radiation therapy, or even with those who already did.

The many new low-carb/Keto breads are an easy way to increase your soluble fiber intake.

1 posted on 10/01/2023 10:39:29 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

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2 posted on 10/01/2023 10:39:58 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Knock on wood. Only very minor issues after prostrate treatment.


3 posted on 10/01/2023 10:45:25 AM PDT by UB355 (inlwess)
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To: ConservativeMind

It seems to me that very article on a medical revelation/breakthrough is really just things that have been common knowledge for years that somebody just got another grant to write another article about.


4 posted on 10/01/2023 10:47:29 AM PDT by E. Pluribus Unum (The worst thing about censorship is █████ ██ ████ ████████ █ ███████ ████. FJB.)
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To: ConservativeMind

.


5 posted on 10/01/2023 12:20:14 PM PDT by sauropod (I will stand for truth even if I stand alone.)
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To: ConservativeMind

Interesting about the keto bread.


6 posted on 10/01/2023 4:03:49 PM PDT by Irish Eyes
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To: ConservativeMind

Interesting, but the sample size in study is very small, only 28 people.


7 posted on 10/01/2023 4:42:20 PM PDT by jimtorr
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To: ConservativeMind

So, they nuke your innards and you get inflammation?.....


8 posted on 10/02/2023 5:53:42 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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