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I have seen manic depression cured by sunshine and/or vitamin D3 directly in three cases, one of them my daughter. The only effective medicine for MD is sunshine (vitamin D). I sent a friend in Việt Nam a year's supply of D3 supplement (VN women hide from the sun for cultural reasons) to deal with her constant flu/cold problems. It fixed the virus chain and I noticed from her emails that her previously severe and getting worse MD was gone. I researched it on line and discovered the MD-Sunshine connection and have since done it for my daughter and a waitress in a diner that I had got to know. I talk about to everybody when the subject comes up, perhaps to the point of being obnoxious, and have heard from several people who had heard me and tried it. It WORKS.