The Israeli Mossad is said to have favored them for assassinations.
Easily suppressed.
The will kill most man sized animals with a properly directed shot to the head.
Shorts will easily penetrate the skull of nearly all man sized animals.
Lots of cows/pigs have been slaughtered with .22 shorts.
The trick is to have the short hit the bone at a close to orthogonal angle, directed at the brain.
The Beretta M-71 is what you seek. You can still find surplus guns but the have pinned fake suppressers to get them imported from Israel. Spare magazines are $$$. The Mossad used this weapon but its in .22 long rifle, not .22 short. What they did was down loaded the cartridge for when the didnt use the suppresser, because it made the package too large for practicality.
All of those assassinations and hog killings are at point blank range.