What I find interesting is the juxtaposition of the fading lions of capitalism, the Venetians, and the new crowd, the Tudors as established by the engine of capital, Henry the VII. In both the “City of Fortune, How Venice Ruled the Seas” and “The Winter King” a study on Henry the VII and the founding of the Tudor dynasty, the close 1490-1510 cooperation between the Venetians and the Tudors is detailed showing how close they were in that age in circumventing the Papal forces in the central Mediterranean and the Muslim control in the east.
I think we can go back to Henry the II almost 400 years earlier to see the beginnings of the Venice-Britain efforts and what they spawned. Columbus, of Genoavise extraction, shipped out of Portugal and Spain as the Genoa Republic competed with the Venetians. The Venetians and the Muslims tied up the Silk Road path from the east and prompted the eastern European nations to round the Horn of Africa and venture elsewhere for a way around that duo.
This article is another confirmation of the capitalistic connection of Venice and Britain leading to the modern era more so than the artistic Renaissance of Florence.
Exactly there was no Indigenous peoples of North or South America, the Pre-Clovis were here, the Siberians came, the Vikings, the Japanese specifically from Island of Hokkaido as proved with DNA studies. The "new world" saw wave after wave of humans from all sides of the planet coming to explore and live, the first cultural/ genocidal war is now though to have been fought between Siberian land bridge people and the Clovis Europeans of the east coast. The DNA is pretty conclusive the east coast Indians are no where near the same genetically as the central and west coast Indians of the America's let alone the southern and meso American ones. Humans made it to Australia 40,000 years ago across open ocean by boat, same for the Polynesian Islands. Humans have had the technology to get to the Americas for at least 30000 years, and the evidence is mounting that people got here not 15000 years ago more like 25k or 30k BCE in pre ice age times.
It is always a pleasure to see someone who knows history, My Great Grandmother was a Doria from Genova of the same Doria's that funded Columbus needless to say we celebrate Columbus day as a family holiday.