I have yet to hear of anyone actually succeeding at opening a door mid-flight. They keep trying though.
Unless you can pull with 8 tons of force you won’t be opening a plug-style airliner door at 8psi differential pressure at cruising altitude. You might have a chance just after takeoff or just before landing.
See question #3:
https://www.johnnyjet.com/ask-a-pilot-lightning-round/