Thanks. Very interesting. This is the area where a very large % of my ancestors settled after they or their parents came to America.
As DNA becomes more of an ancestor tracking tool, we may see some interesting results from people whose ancestors settled in this area.
Having said that.
Family myths have a way of getting destroyed by DNA. Supposedly, many of my clan from that area were related to Princess Lie A Lot. So far zip Cherokee or any Indian DNA has shown up.
https://www.roadsideamerica.com/story/51476
I had basically zero of that, and expected zero (ditto for Africa). OTOH, I also rely a lot on family stories. Often, the really juicy ones don't survive in one's own family line, but are remembered in the collateral lines, or by other families in the same small town if both families stick around long enough (we've been here for more than 170 years. A lot of oral information must have been lost by this time.
There are a lot of people who appear to be very disappointed that there's no DNA from Tribal Americans when they get their reports. I've seen comments on the Ancestry board about this, and seen articles about it. Some of the time that's because there have been three or more generations since the last "known" potential source, and as there is no sample of that person's DNA, there's no telling how much they themselves had. The French were getting established by the 1580s, the the English Roanoak "Lost Colony" in 1585 and Jamestown in 1607, and the Dutch first arrived in 1624 -- and often, 400 years takes a lot of generations to fill.