Beyond the problem with investigations, which I think is the biggest challenge, I think that we will find it a net plus. Trump is a negotiator, and Ryan and his losers or obstructionists, not negotiators. We might not be happy with some of the trade-off, but Trump will take this in stride and use it to his advantage. Keep in the senate is far more important.
At least the situation is now simplified with the RINO saboteurs out of the picture.