Posted on 10/28/2019 3:54:31 PM PDT by SunkenCiv
People who take all of their blood-pressure medication in one go at bedtime are better able to control their condition and have “a significantly lower risk of death or illness” caused by heart or blood vessel problems compared to those who take their anti-hypertensive medication in the morning, according to research published this month in the peer-reviewed European Heart Journal.
The trial instructed 19,084 patients to take their pills on waking or at bedtime, and followed them for more than six years — during which time the patients’ ambulatory blood pressure was checked over 48 hours at least once a year. The results were adjusted for age, gender, Type 2 diabetes, kidney disease, smoking and cholesterol levels.
The researchers found that patients who took their medication at bedtime reduced by 45% their risk of dying from or suffering heart attacks, myocardial infarction, stroke, heart failure or requiring a procedure to unblock narrowed arteries, compared to those who took their medication after waking up in the morning.
The risk of death from heart or blood vessel problems was reduced by 66%, the risk of myocardial infarction was reduced by 44%, coronary revascularization (unblocking narrowed arteries) by 40%, heart failure by 42%, and stroke by 49%. However, the researchers noted there are no studies showing that treating hypertension in the morning reduces the risk of cardiovascular disease.
(Excerpt) Read more at marketwatch.com ...
My heart has a beat and I can dance to it.
The evening is when I take mine. I just want to weather any drowsiness that it might cause while I’m sleeping.
That is astonishing — a 45% risk reduction by taking it at night rather than in the morning.
There must be other factors at work. That risk reduction just seems WAY too big. Maybe the people who took their medicine in the morning are not as reliable at taking it as those who take it at bedtime.
I take mine just before turning in. I really enjoy how the diuretic blood pressure medicine reminds me to wake up and pee during the night. ;>)
Just kidding. I usually sleep through the night without having to go to the bathroom. Hallelujah!
No, I think there’s something to it. I know I seem to sleep better (wake up feeling better-rested) when I take it just before bed, rather than taking it before work. Not that I sleep at work. Y’know, if anyone is watching.
It’s a good thing to know about, I’ve only had to start taking the pill a bit more than a year ago.
I have my dose split into two tablets. I take one in the morning and one at night.
I might try both at night.
Seems like more danger of dying at night.
I take mine when my doctor tells me to...two in the morning, one after supper, and a final one at night.
My doc told me to take it first thing in the morning.
Figures.
BUT... Did they interview anybody who did NOT take it at night?
Maybe they live longer because they get all that exercise running to the bathroom during the night.
The article doesn't say what anyone's blood pressure was or how many deaths occurred in their trial group.
Pretty thin gruel, IMHO.
ML/NJ
Wonder if it’s related to cortisol levels rising in the early morning hours.
I take two BP meds.
One - the “water pill” I take in the morning between 8 and 9.
The second med I take in two doses, one between 11AM and 12PM and the second dose between 11PM and midnight (roughly noon and bedtime). I have found the second pill taken twice in a 24 hour period at the dosage I use works better than did a double dose taken once a day.
Splitting it up and taking half as much twice a day makes for a more steady amount of that BP med in the blood stream than taking it all at once. At the dosage I take it is known to lose it’s positive impact in less than 24 hours, but still has sufficient impact at 12 hours in.
I did not know any rationale for setting up my 12 to 12 split between those two doses. I did it because one at noon and one at bedtime seemed practical to me.
A retired cardio RN gave me a heads up on this study.
I now take my Tenormin before bed. I seem to sleep better and the data on this study is impressive.
A lot of good benefits with the same drug by changing the dosing from morning to bedtime.
“My doc told me to take it first thing in the morning.”
Sounds like a good reason to take it at night, given the medical community’s record on giving advice regarding things they’re clueless on.
My metoprolol and lisinopril will now be taken before bed which is 2am for me at the earliest
I’ve got a low dose of the, uh, lisinopril? and the water pill is also in there.
I take my blood pressure in the morning with a wrist cuff before taking my Amlodipine and take my pressure 2 hours later. It's always lower and within norms. Another study, another conclusion. I've lost all faith in scientists. BTW, red meat is bad. No, red meat is good. Wait! Eggs will kill you. Uh, not so much.
My daily routine pushing 70:
Morning is 2-3 cups of coffee and 2 pills of Milk Thistle (I drink), my Amlodine and Armour for thyroid. A cup of Fiber One with 2% milk.
Afternoon: Walk on treadmill with 3% angle 3 times a week or work around the house in between. Take multi-vits without Iron (males), Saw Palmetto (never pee at night), Vitamin D.
Dinner: Chicken mixed with some Mayo salad on Triscuits with small slices of cheese. I cheat with a bacon cheeseburger about once a week.
Yearly: I have a comprehensive blood work done and the only thing that shows outside of the norms is triglycerides. I'm always amazed the my liver enzymes are within norm. European doctors prescribe Milk Thistle for liver health. I've outlived both my parents and grand-parents so far. Don't want to live forever, but glad I feel like I'm 50 rather than 70.
Here's the ticket gentleman. I also get bio-identical testosterone injections every couple weeks. Ever wonder why young men don't get as many heart attacks or strokes? It costs me $30 twice a month and the best thing you can do for your health if you're over 50. Google it and find out the benefits. You'll feel more energetic, amorous, and your mate will love it. Forget the stupid pills on the commercials.
I was told that, too. It was followed by, "Unless you like to get up several times to pee." That, for me, is a restless night. Sometimes I can't get back to sleep.
I imagine the actual blood pressure med could be at night and take the pee "pill" in the morning. If not the best, I'm guessing it's better than both in the morning.
Of course, this assumes that this research is accurate.
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