Your talking starting with pre made amino acids. Put 10^378:1 into perspective there are 10^89 atomic particles in the universe if you include photons. And there are 10^18 seconds. The average size protein has about 600 amino acids and the smallest human chromosome has 1 million.
But it’s all by accident, they tell us. And for no explainable reason, those elements got together and formed amino acid molecules, which got together to form proteins, which got together to form chromosomes, which came to life. And then that living cell got more and more complex until the single cell creature became a human.
All of which violates Newton’s Second Law of Thermodynamics which states that any isolated system ALWAYS degenerates to a more disorganized state.