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Hmmm. “McGovern Commission might have been a clue”. I guess that’s why I have never heard of the sulfur cycle.

Our Immunology course was even worse than Lehninger (actually Lehninger was about 400 pages in the first edition, which I still have. Our “White Cell Manual” literally was a Pamphlet. Literally. 60 pages with cardboard cover. LOL. All the early experiments on immunology. It was a lecture during Microbiology. I would imagine Immunology is it’s own course now.

Seven years ago I was new at this. My wife ask me (honey do) to look into PKAN. We found a very large cluster in the Caribbean because of one of her residents.

My professional background was failure analysis and systems studies. It blew up, fell down, shut down or sunk kind of thing. It took me nearly everywhere.

Honey do means do and I liked the change.

I was lucky enough not to have studied the problem conventionally. I went back to the beginnings and that started with Novelli and not Fritz Lipmann. Lipmann was awarded the Nobel prize for the discovery of the CoA pathway. Novelli actually did the work on some of the protein entrances to it. It was this that led us to the cycle. I think Lipmann's discovery was in 1945. People have been stuck in that paradigm. It was very easy for us with miRNA studies to step out of it and show how protein expression was not chiseled in stone and was easily changed.

A very long strange trip.

Best. I have been putting off working on references tonight. I just don't feel like it. Time to sleep.