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I need this explained to me: Why is Remdesivir an improvement over HCQ/Zinc/Antibiotics?
4/17/2020 | Vanity

Posted on 04/17/2020 6:20:15 AM PDT by RinaseaofDs

We have an effective therapy, have had it since before 2009. Fauci begged to use HCQ during the MERS outbreak in 2009.

Now we have SARS-2, the Wuhan Boogaloo. We have a MOUNTAIN of empirical evidence that HCQ/Zinc is prophylactic and HCQ/Zinc/Antibiotic is a therapy for the infected.

Remdesivir is tested on 125 people with good results (and two deaths), but NOW there's hope?

Sorry, smells horrible.


TOPICS:
KEYWORDS: coronavanity; hcq; hcqzpaczinc; moremoney; patent; remdesivir
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To: Chauncey Gardiner
Many bogus studies out now testing HCQ without Zinc and Z-Pack. Surprise surprise, results are “not as effective” .

Furthermore the combo is not given at the onset of symptoms as species in the protocol, but much later.

81 posted on 04/17/2020 8:01:22 AM PDT by The Truth Will Make You Free
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To: kiryandil

He He! Both your comment and your tag line are hilarious.


82 posted on 04/17/2020 8:01:33 AM PDT by Aevery_Freeman (AOC has the perfect face for the 'Rat Party - Hee-Haw)
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To: usconservative

Alternatives to HCQ/Azithromycin are needed...
_______________________________
I have read of substituting doxyxycline. All I have read is that doxy stops bacterial replication. Also, mega doses of Vit. C ‘to bowel tolerance’ is being used.


83 posted on 04/17/2020 8:04:43 AM PDT by reformedliberal
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To: Mom MD

The gestalt among frontline physicians is that the hydroxychloroquine/Zithromax treatment with the observed clinical benefit and decline in C Reactive Protein is most likely to be seen if the treatment is begun with the earliest onset of symptoms of fever and dry cough. If it is delayed until shortness of breath, actual pneumonitis or a COVID-19 confirmatory test is in hand, it is less likely to be effective. Try to post accurate information. If a patient requires hospitalization, the death rate regardless of therapy is quite high, probably close to 70% in intubated patients.


84 posted on 04/17/2020 8:07:47 AM PDT by allendale (.)
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To: exDemMom

Your DNA would not be sequenced in an assay designed to detect Covid-19 RNA.
___________________________________________
Both involve swabs. Could DNA be extracted from the raw swab prior to sequencing?


85 posted on 04/17/2020 8:08:54 AM PDT by reformedliberal
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To: RinaseaofDs

If that happens there is going to be a lot of new daddy’s and you’re not my daddy!

lol sort of.


86 posted on 04/17/2020 8:11:14 AM PDT by US_MilitaryRules (I'm not tired of Winning yet! Please, continue on!)
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To: Moonman62

Not only is it not a Trump pill, it’s Soros pill, he is making money off it.


87 posted on 04/17/2020 8:12:21 AM PDT by MomwithHope (Forever grateful to all our patriots, past, present and future.)
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To: kiryandil

If that is the case, Trump will make it generic. Everyone can make it.


88 posted on 04/17/2020 8:13:01 AM PDT by US_MilitaryRules (I'm not tired of Winning yet! Please, continue on!)
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To: Black Agnes

exactly!


89 posted on 04/17/2020 8:13:50 AM PDT by griswold3 (Democratic Socialism is Slavery by Mob Rule)
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To: TBall; All

The poster is a fraud, not an MD, Christian in name only, possesses a modicum of clinic experience as an assistant, has no clinical trial experience, is pushing vaccines that are not tested, doesn’t explain their mechanism of action (or will advance a sales pitch written by liars to sound convincing), believes a vaccine will treat dying hospitalized patients which is not the purpose of a vaccine, refuses to defend false assertions with supporting facts, dismisses solid statements in support of HCQ combination treatment by real MDs who are expert in virology.

Dr. Stephen Smith, M.D., Internal medicine - infectious disease, Diplomate in Virology:

‘Hydroxychloroquine is a game changer and the beginning of the end coronavirus pandemic,’ Infectious Disease Specialist Dr. Stephen Smith says

https://techstartups.com/2020/04/01/hydroxychloroquine-game-changer-beginning-end-coronavirus-pandemic-infectious-disease-specialist-dr-stephen-smith-says

Dr. Smith is only ONE of dozens, of a group growing every day of esteemed, transparent, proven, medical scientists and practitioners who have seen the benefits if HCQ combination therapy backed by real data and practice.

Let the frauds who call themselves Christian who kiss the behinds of Gilead Sciences and other Gates funded population control vaccine laboratories reveal themselves and stand up to real MDs and scientists who have observed and share real data of the benefits of HCQ combination therapy. They won’t, they will not defend their assertions with data, they will not defend their propositions with real data, regimens, and experience because such defenses would reveal arguments their lack merit having an agenda that poses as medicine but is in truth one of stock options for the ignorant startup puppet, one of population control for the puppetmaster. You will see such false advocates point to the commencement of recent clinical trials of HCQ without noting the omission of combination medicines and antiviral nutrients, without noting the protocols of such trials are written by offices with Directors that are tied to the Gates Foundation and who have patents on SARS engineered viruses and vaccines that are prima facie evidence of conflict of interest:

https://patents.justia.com/inventor/anthony-s-fauci

The frauds will not defend vaccines without revealing a lack of scientific acumen and medical maturity, they will instead attack a combination of drugs with records older than they are and which have expired patents negating obscene profits but which are in widespread use today with minimal side effects, yet they will demonize hydroxychloroquine sulfate as having ominous side effects without revealing the side effects are the same as aspirin (WebMD).

A gaggle of Gilead lab workers are frequently found on social media casting aspersions on HCQ, drawing attention to poorly designed underpowered results of HCQ on dying patients, analogous to an overdosed heroin addict rushed to the ER and treated with buttermilk for a diagnosis of acid reflux disease. When the addict dies, hospitalists record the buttermilk was ineffective in treating the acid reflux.

Such ‘reports’ are garbage but CNN and others will report then as gospel.

There is an agenda in these Gates backed pharma companies:

Stock market live updates: Dow jumps 500 points, Cramer says Gilead drug gives us a ‘fighting chance’
https://www.cnbc.com/2020/04/17/stock-market-live-updates-dow-futures-jump-cramer-says-gilead-drug-gives-us-a-fighting-chance.html

And for the true and concerned Christians, remember, Satan will tell you the truth nine times straight, draw you in, then drop the LIE on you.

Do not judge, let events unfold before you, God is in control.


90 posted on 04/17/2020 8:14:43 AM PDT by Hostage (Article V)
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To: RinaseaofDs
Remdesivir may -- or may not -- overall be more effective or safer than the HCQ/Zinc/Antibiotics combination. Or different drugs will be better for patients at different stages or with different medical histories. The point of clinical trials and competitive evaluations is to find that out. There may be some other drug that is even better like ivermectin, or a biologic like blood plasma from convalescent patients, or some other therapy entirely. One count lists more than 160 drugs and vaccines in development. Vanquishing the Virus: 160+ COVID-19 Drug and Vaccine Candidates in Development.
91 posted on 04/17/2020 8:14:52 AM PDT by Rockingham
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To: Rockingham

I don’t dispute anything you are saying. More cures are better, especially in the realm of virology.

However, why a 900 point move to the upside in the market, and the breathlessness of the people reporting it in the media?

The risk involved in a novel treatment like this is orders of magnitude higher than with HCQ/Zinc which Fauci has been throwing shade on since the get-go.

The entire reason we have an FDA is Thalidomide. Great drug, and then over time you find out it maims kids in the womb.

HCQ is relatively safer, by a wide margin. Why the continuing shade?


92 posted on 04/17/2020 8:19:15 AM PDT by RinaseaofDs
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To: RinaseaofDs

Follow the money.


93 posted on 04/17/2020 8:23:51 AM PDT by JimRed (TERM LIMITS, NOW! Build the Wall Faster! TRUTH is the new HATE SPEECH.)
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To: reformedliberal
I've been heavily ingesting natural Vitamin C (Oranges, tangerines, natural orange juice) to boost my own immune system, also been taking Vitamin D and K supplements for the same reason.

Knock wood, so far so good. I have a repressed immune system due to an inflammatory genetic condition so boosting my immune system is very high on my list starting in October through April anyway. I also take extra precautions (washing hands, keeping hand sanitizer on me, not touching my face) for the same reason. I'm pretty well self-trained in all the things the experts are telling us to do to avoid the China virus already.

I think it's well past time for the country to get back to work. People like me know what we need to do to take care of ourselves and not get sick. The burden of that shouldn't be on the rest of the country.

Just my own .02.

94 posted on 04/17/2020 8:27:53 AM PDT by usconservative (When The Ballot Box No Longer Counts, The Ammunition Box Does. (What's In Your Ammo Box?))
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To: Mom MD
IF used early in symptoms the HCQ + Zinc + AZ does reduce the viral load. You are referring to hospitalized patients. Such patients are being over run by the viral load, which has reached the point of attacking the organs not just the lungs, lungs which are already heavily damaged. To expect the Trump pills to repair the damage is unrealistic.

HCQ acts to reduce inflammation in the airways, but it does ferry ZINC into the infected cells which have not died, so it does reduce viral load, especially effective if the symptoms are treated early on. And that's the way this cocktail will help get the nation back at work ... if the drug cocktail is allowed to be written by any physician or physician's assistant before hospitalization is needed.

As you know, the virus attacks via the ACE2 receptors. Once a person is hospitalized, the virus is raging throughout the body, attacking not just the lungs but the organ systems, too.

95 posted on 04/17/2020 8:29:02 AM PDT by MHGinTN (A dispensation perspective is a powerful tool for discernment)
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To: RinaseaofDs

It may help if your stupid governments won’t let you start the Trump pills soon enough for their best results. Always good to have a plan B, just look at Rush’s cancer battle.


96 posted on 04/17/2020 8:33:11 AM PDT by JohnBovenmyer (waiting for the tweets to hatch)
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To: RinaseaofDs
Remdesivir is closer to approval for COVID-19 therapy because it was developed as an intended HIV remedy. It flunked effectiveness trials for HIV but passed as safe in that context. Depending on Remdesivir's detailed mechanism of action, it could be projected to be a safer and more effective antiviral than the HCQ/Zinc/Antibiotics cocktail. From what I have read, that therapy works best if administered before breathing is impaired in a major way. It may be that Remdesivir could work even in such advanced cases, just as Ivermectin is said to do.

Nevertheless, the larger issues of the slowness of the FDA approval process and the distorted incentives in drug development remain. With a mandate to help develop new drugs, the FDA loves Remdesivir, the new, bright and shiny thing, but scorn old, previously approved remedies like HCQ/Zinc/Antibiotics and Ivermectin. The stock market seems to recognize that and is cheered by the advance of Remdesivir through the FDA approval process.

97 posted on 04/17/2020 8:44:30 AM PDT by Rockingham
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To: upchuck

Hey, IF remdisivir destroys the virus throughout the body, for acute patients, the cost is irrelevant because it is weighed against losing the patient to death. I don’t knock ANY medicine which can save a very serious patient from death. BUT the HCQ cocktail is not aimed at those patients. It is very effective when used early, treating the early diagnosed aggressively. The newest ests will make that treatment be very effective, IF the HCQ is allowed to be written by all physicians in any treatment setting.


98 posted on 04/17/2020 8:49:13 AM PDT by MHGinTN (A dispensation perspective is a powerful tool for discernment)
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To: Balata

Best answer yet. Kudos


99 posted on 04/17/2020 8:51:54 AM PDT by MHGinTN (A dispensation perspective is a powerful tool for discernment)
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To: Mom MD

Your opinion is beginning to sound more like an agenda than an opinion. The proven effectiveness of HCQ and ZINC is from PRE HOSPITALIZED patients. Sadly, I don’t think ANY drug is going to reverse the extensive organ damage found in the patients needing a ventilator. But you can keep hoping for one ... the efficacy of HCQ + ZINC + AZ or doxycycline in pre-hospitalized patients is not the question you keep addressing.


100 posted on 04/17/2020 9:07:23 AM PDT by MHGinTN (A dispensation perspective is a powerful tool for discernment)
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