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Compare randomized controlled trials to another very common type of study known as a "retrospective study." A retrospective study enables researchers to examine events that have happened in the past. For example, take a recent retrospective study that compared patients who were hospitalized with COVID-19 and treated with hydroxychloroquine to patients who were not treated with it.

The study found a lower mortality rate among those patients who took hydroxychloroquine. But these types of studies have a number of limitations, the most important being bias. Specifically, physicians might be prescribing hydroxychloroquine for those patients most likely to do well with the drug and not prescribing it for those they believe it will not help. That alone may explain why the study found that patients taking hydroxychloroquine did better.

1 posted on 09/18/2020 8:55:16 AM PDT by SeekAndFind
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To: Mrs. Don-o; tellw; Huskrrrr; Jane Long; Freedom'sWorthIt; Freedom56v2; BDParrish; Phx_RC

Ping as per your request


2 posted on 09/18/2020 8:55:53 AM PDT by SeekAndFind
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To: SeekAndFind

Because. Trump.....................


3 posted on 09/18/2020 8:58:39 AM PDT by Red Badger (Sine Q-Anon.....................very............)
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To: SeekAndFind

It is amazing the people who don’t understand this, and the nature of double blind experiments, who still think they are qualified to have an opinion.


4 posted on 09/18/2020 9:07:51 AM PDT by RedStateRocker (Nuke Mecca. Deport all illegals. Abolish the DEA, IRS and ATF,.)
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To: SeekAndFind

Where are the randomized controlled trials showing the efficacy of cloth or paper masks? The only peer reviewed studies I’ve seen say they are ineffective.


5 posted on 09/18/2020 9:12:19 AM PDT by circlecity
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To: SeekAndFind

So ... where’s the randomized controlled trials for mask-wearing and ‘social distancing’?


6 posted on 09/18/2020 9:15:21 AM PDT by bassmaner (Hey commies: I'm a white male, and guilty of NOTHING! Sell your 'white g uilt' elschewhereive)
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To: SeekAndFind

When did they hold the randomized, controlled trial on whether or not masks are effective against the virus?

What, they didn’t??


10 posted on 09/18/2020 9:19:38 AM PDT by Buckeye McFrog (Patrick Henry would have been an anti-vaxxer.)
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To: SeekAndFind

A Dr who is reporting astounding field success with ivermectin treatment points out that RCT would actually be unethical, to withhold treatment with a high rate of success and potentially let untreated patients die....in the name of science. Ditto with HCQ.

Fauci the bureaucratic scientist who treats no patients....has no such moral qualms.


12 posted on 09/18/2020 9:33:43 AM PDT by silverleaf (A live Biden speech is like a solar eclipse: rare, and leaves everyone in the dark)
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To: SeekAndFind; All

Back room fighting over juicy government contracts, aka, chasing the money?


15 posted on 09/18/2020 9:46:38 AM PDT by Amendment10
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To: SeekAndFind; Liz; bitt; LucyT; LS; Travis McGee; bagster; Jim Robinson; All

https://en.wikipedia.org/wiki/Sildenafil

How EVIL & BIG is BIG PHARMA? WHO and WHAT can THEY BUY?

https://www.youtube.com/watch?v=oMeulTWdqiY

PFIZER...Bob 1st person speaking Dole. Landmark SC case Kelo vs Connecticut.

https://en.wikipedia.org/wiki/Kelo_v._City_of_New_London

How is it that Pfizer spinoff...animal vaccine maker Zoetis recently opened up another lab in CHYna?

Hearings? Crickets. Alt-media (right or left)? Crickets. ANY MEDIA OR INTERNET? F’n CRICKETS. FYI patriots.

https://www.youtube.com/watch?v=K8E_zMLCRNg

Politicians for sale. Robes for sale. Citizens for sale.

Blue pill? Red pill? No matter...take BIG PHARMA pill. DON’T READ the side effects. That’s their “plausible deniability”.


17 posted on 09/18/2020 9:57:04 AM PDT by PGalt (Past Peak Civilization?)
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To: SeekAndFind

Yes its best to get a double blind, meaning both doctors and patients don’t know who gets the drug and who do not. And its best to get it randomized, meaning the groups are not in any way self selecting. But this critique was used to merely cast dispersions at HCQ because the tests were not perfect. They leave out the fact that the disease was so new, there was no time to run a “perfect” study. So they looked for evidence within the data they had. And in that data they found lots of evidence that HCQ works in lowering the deaths if the dose is normal and its taken as soon as symptoms start. In almost all of those studies there is a positive effect and in some there is no effect.

But almost all the antivirals including HCQ work about the same. However, Zinc and vitamin D also work as well. And the combination works best. There are some other vitamins and drugs that can help as well. But the combination of these three are extremely helpful in reducing the fatality and ICU rates to near zero.

And this fact which is known and understood by most doctors has changed the situation in a few ways. Firstly nurses and doctors have been using this formula for 6 months. Secondly the fatality rates have gone down significantly. Such that, if you see a fatality rate after June 1st it is far lower than before June 1st. Even in people 80+ the fatality rate goes from 30% in April down to 10% in August. And in those below 40 the fatality rate is below the flu or car accidents or even the fatality rate excepting Flu, Covid and car accidents. So just walking around is far more dangerous than getting Covid.

But getting back to HCQ, there are now some good studies that are both double blind and randomized that do show that HCQ works in reducing death. And now the blow back is that the studies are not big enough. But thats because the studies are ongoing and they will magically become valid right after the election.


28 posted on 09/18/2020 11:09:36 AM PDT by poinq
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To: SeekAndFind

Now, let us see the clinical controlled studies verifying the effectiveness of facemasks.


29 posted on 09/18/2020 11:12:17 AM PDT by upsdriver
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To: SeekAndFind
"Physicians and scientists said that randomized controlled trials involving the drug would be needed before we could know whether it was an effective treatment."

Randomized controlled trials are indeed the gold standard WHEN YOU HAVE A MINIMAL AMOUNT OF DATA. There are now HUNDREDS OF THOUSANDS OF DATA POINTS that demonstrate that hydroxychloroquine, particularly when given early and supplemented with zinc and antibiotics, saves lives - thousands of them. Statistical analysis is irrelevant. Hydroxychloroquine works! The only people disputing that are politically motivated and not scientifically literate.

31 posted on 09/19/2020 2:32:15 AM PDT by norwaypinesavage (Calm down and enjoy the ride, great things are happening for our country)
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To: SeekAndFind

NY ran a real world where wealthy and politically connected (plantation owners) were given the hydroxycloraquin protocol and the plebs were sent to nursing homes.


33 posted on 09/20/2020 7:45:32 AM PDT by fella ("As it was before Noah so shall it be again,")
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To: SeekAndFind

Because OrangeManBad.


36 posted on 09/20/2020 7:48:53 AM PDT by AppyPappy (How many fingers am I holding up, Winston?)
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